Equine Anesthesia Flashcards

1
Q

general info

A

Most commonly anesthetized of all large animals
temperment and size pose a challenge
Stallions: penile prolapse/priapism from ace
Xylazine abortion in 3rd trimester

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Common procedures

A

Colic
arthroscopy
castration
upper airway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Prep

A

Clinical exam

Lab tests

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Clinical examination

A

hx
basics:
HR, RR, mm (color & CRT)
hydration status

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Lab tests

A

Basic hematology and biochem:
PCV, TP, urine SG
compromised patients require more specific laboratory tests

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Venous catheterization

A
usually jugular vein 
Aseptic prepping of site
Local anesthetic infiltration
Catheter placement, 12 gauge (adult horse)
Suture catheter to skin with nylon
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Preanesthetic preparation

A

Starve for 4-6 hours
Withhold water for at least 2 hours
Pull out all horse shoes
Rinse mouth with pressurized water to clear foreign matter that might attach to endotracheal tube and possibly contaminate/infect lungs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Premedication

A
Analgesia
Butorphanol
Methadone/morphine
A2 adrenergic drug (xylazine, romifidine, detomidine)
Flunixine meglumine 1.1 mg/kg
Meloxicam
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Considerations during premedication

A

preferably in an induction (-cum-recovery) box
Padded stall, swing door, tiltable table
Restrain horse properly during induction
quiet environment
effective communication within the team
be sure sedation (including muscle relaxation) has taken full effect before administering induction drug (ketamine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Induction

A

Advisable to administer a muscle relaxant before the induction agent
-GGE
-Benzodiazepine: diazepam or midazolam
Ketamine 2.2 mg/kg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Intubation

A
26mm diameter tube for average 500 kg horse
mouth gag to pull jaws apart
neck extended 
lubricate tube
intubate blindly- easy
inflate cuff
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Positioning on theatre table

A

Depends on type of sx
cushion pressure points (head, shoulders, pelvis)
stretch and spread apart limbs- to encourage blood flow
Protect eyes from trauma, pressure
Turn while changing body positions slowly
Keep in only one lateral recumbency throughout

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Maintenance

A

Isoflurane, sevoflurane
Large animal circle anesthetic circuit required
Oxygen flow rate: 20ml/kg/min soon after induction (30-60min) and towards recovery; 10ml/kg/min during maintenance
Mechanical ventilation (IPPV) recommended esp if anesthesia time longer than 45 min
IV drugs for partial or total anesthesia
Make use of local anesthetic drugs and techniques as much as possible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

PIVA and TIVA

A

most IVA protocols in horses combine:
A2 adrenergic drugs (xylazine, detomidine, romifidine, medetomidine)
Muscle relaxant (GGE, midazolam)
Hypnotic agent (ketamine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Maintenance PIVA

A
combination of inhalational and IV drugs
attainment of balanced anesthesia
Goals: 
MAC (inhalation agent) reduction
Analgesia provision
Vital system adverse effects reduction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Maintenance: TIVA advantages

A

Less cardio system depression
Superior analgesia
less likelihood of movement in response to surgical stimulus
decreased surgical stress
lower morbidity and mortality
better quality of recovery from anesthesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

TIVA: field maintenance

A

TIVA protocols commonly known as
Triple drips
Double drips effective as well
Include any possible local anesthetic techniques for maintenance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

TIVA

A

alternatively top up with intermittent boluses
Ketamine about 0.4 mg/kg
Diazepam or midazolam 0.1 mg/kg
a2 adrenergic agonist (xylazine, deromidine, romifidine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Monitoring

A
Anesthetic depth
Resp
Cardio
Regular arterial blood gas
Thermoregulatory
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Anesthetic depth

A

CNS
Surgical: weak palpebral reflex/anal tone
too light: lacrimation, nystagmus, movement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Respiratory system

A

RR and depth (TV)

hypoventilation likely: IPPV mostly needed; asses ETCO2 (expired CO2)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Cardiovascular system

A

Hypotension common: direct blood pressure

ECG lead I as for ruminants

23
Q

Regular arterial blood gas measurements

A

Hypercapnea (high PaCO2)

hypoxemia (low PaO2)

24
Q

Ideal anesthetic depth

A
weak palpebral reflex
no nystagmus
weak anal tone
Stable autonomic reflexes
non-responsive to noxious stimulus
25
Q

Too light

A
Blinkng
lacrimating
nystagmus
corneal reflex present
tachypnea, tachycardia
movement of limbs/neck in response to surgical stimulus
26
Q

Too deep

A

Absent palpebral reflex
absent corneal reflex
dry cornea
bradypnea, apnea, bradycardia, hypotension

27
Q

Recovery from anesthesia

A

Highest risk period of equine anx- characteristically excitable ‘flight’ animals and myopathy risk
soft-padded, non-slip recovery boxes
dim light and quietness in recovery boxes
sedate with a2 adrenergic agonist (romifidine) to delay standing attempts
nasotracheal intubation
supplement o2
keep same lateral recumbency from in sx- sacrifice only one lung side to inevitable atelectasis
may be supported with robes or left alone in recovery box
Analgesia
temperature control

28
Q

Techniques used in assisted recovery

A
manual assistance within recovery box
head and tail rope recovery
-deflating air pillow
-sling recovery
-pool recovery
29
Q

Complications

A
sudden heart failure
hypotension
hypoventilation
hypoxemia
myopathies: postanesthetic rhabdomyolysis
Myelopathies: esp radial n, obturator n, facial n
excitement and ataxia
nasal obstruction
jugular vein thrombosis
30
Q

Hypotension: treatment options

A

MAP < 70 mmHg; SAP <90 mmHg
treat specific underlying cause
reduce administration rate of anesthetic drugs, if indicated
volume resuscitation (crystalloids 10 mL/kh; colloids 5mL/kg; blood- if hemorrhagic)
cardio-active drugs: dobutamine, ephedrine etc

31
Q

Hypoventilation management

A

mechanical ventilation
set RR and volume (pressure)
target 35-45 mmHg expired CO2

32
Q

Myopathy in horse

A
Most common cause of morbidity/mortality during horse anesthesia
various types of myopathies arising from different causes
Anesthesia associated myopathies
with rhabdomyolysis
-compartmental myopathy
-malignant hyperthermia
Without rhabdomyolysis
-hyperkalemic periodic paresis
33
Q

Myopathy– clinico-pathological changes

A
myoglobinuria & hyperglobinemia
muscle enzymes (CK, AST, LDH elevated)
electrolytes (P & K elevated, Na, Cl, Ca decreased
BUN and creatinine elevated
CBC: inflammatory leukogram
34
Q

compartmental myopathy- predisposing factors

A

muscle and nerve tissue ischemia associated with poor perfusion

  • heavily muscles horse: >600kg
  • fit or nervous horse
  • persistently low MAP: <70 mmHg
  • improper positioning: perioperatively
  • prolonged anesthesia (recumbency) time: > 2hours
  • halothan maintenance
35
Q

compartmental myopathy- signs and symptoms

A

6 ps (pain, paresis, paralysis, palloe, pulselessness, poikilothermia)
failure to stand on specific muscle group: forelimb, hindlimb
muscle feels hard (tense and firm) and is severely painful
Myoglobinuria and subsequent renal failure

36
Q

compartmental myopathy- treatment

A

symptomatic:
-fluids
-analgesics, muscle relaxants &/or sedatives
-o2 radical scavengers:DMSO
-PT
-tender love and care
Fasciotomy-decompression

37
Q

Malignant hyperthermia: predisposing factors

A

life-threatening skeletal muscle pharmaco-genetic disease
humans, pigs, horses susceptible- rare
mutations in ryanodine gene causes dysfunctional release of excessive calcium into sarcoplasm
-halothane
-stress
-depolarizing muscle relaxants (succinyl choline)
-improper positioning: laying on hard surface, legs compressive each other for too long, etc

38
Q

Malignant hyperthermia: signs and symptoms

A

hyper-metabolic state: hyperthermia, hypercapnea, lactic acidosis

  • profuse sweating
  • tachypnea
  • tachycardia and arrythmias
  • hypertension
  • prolapse of third eyelid
  • flared nostrils
  • contracted masseters
  • muscle rigidity and twitching
  • myoglobinuria
  • death and per acute rigor mortis
39
Q

Malignant hyperthermia: prevention

A

correct positioning and padding
pre-anesthetic dantrolene in susceptible
maintain normal blood pressure

40
Q

Malignant hyperthermia: treatment

A
dantrolene
water/alcohol baths
ACP for vasodilation
Na+ bicarb for acidosis
TLC
41
Q

Hyperkalemic period paralysis (HYPP)

A

Rare genetic trait that affects quarter horses (most commonly), less commonly in Appalosas and their crosses
Mutation results in failure of Na+ channels to deactivate- excessive Na+ influx and K+ outward flux in mm cells
Episodes can be triggered by:
-transportation
-stress
-sedation
-anesthesia

42
Q

Hyperkalemic period paralysis (HYPP)- signs and symptoms

A
can be a challenge to intubate
might develop myopathy at recovery 
-respiratory distress, laryngeal paralysis
-swaying
-staggering
-dog-sitting
-recumbency 
-prolapse of eyelid
43
Q

Hyperkalemic period paralysis (HYPP)- treatment

A

increase K+ excretion by:

  • ace
  • dex
  • Ca gluconate
  • TLC
44
Q

Neuropathy- general info

A

commonly concurrent with myopathy
Ischemia, pressure and stretching possible causes
nerves on dependent weight bearing parts
-facial, radial, spinal malacia (draught horses- always fatal)

45
Q

Neuropathy- prevention and tx

A
correct positioning and padding
Remove head halter during anesthesia
Maintain normal blood pressure
not painful
nerves may revitalize once swelling
subsides
symptomatic treatment
TLC
46
Q

Nasal edema

A

due to gravitational (hypostatic) fluid extravasation which then restricts diameter of nostrils
place nasal tube until horse stands- otherwise risk horse will panic at threat of asphyxiation and try to jump up prematurely
oxygen supplementation

47
Q

Excitement during recovery

A

Minimize stimulation during recovery
sedate with romifidine/detomaidine/xylazine to delay attempts at standing. romifidine causes least ataxia
excited horses may suffer bone fractures
re-anesthetize to repair fracture or euth

48
Q

Foal

A

Presents a different challenge from adult
be aware of physiological differences
Premed in presence of mother
Benzos are v effective sedative in foals
may combine with butorphanol for analgesia

49
Q

Foal induction and maintenance

A

inhalation induction: through nasotracheal tube or face mask
inductionL propofol, ketamine
isoflurane, sevoflurane, for maintenance

50
Q

Foal-recovery

A

usually requires some human physical support during recovery

  • delay attempts at getting up by keeping down manually
  • support head and pull on tail base once up
51
Q

Donkey

A

Stoic animal
fight rather than fright and flight
thick skin over jugular furrow
cut down for venous catheterization

52
Q

donkey- drugs

A

less prone to excitement during induction or recovery periods
more resistant to sedatives, anesthetics and analgestics- inc dose by 30%
ketamine half life also shorter
anticipate more frequent top ups
more sensitive to GGE

53
Q

donkey-recovery

A

smoother than the horses
rarely noticeable emergency delirium/excitement
nasal tube may be used to counter adverse effects of nasal edema
human physically assisted recovery: watch out for kicks