Equations Flashcards
1
Q
Volume of distribution (Vd)
A
Vd = (dose x f)/Cp
f = bioavailability
Cp = concentration of plasma
2
Q
Clearance (CL)
A
CL = dose rate/ Cpss
Cpss = Contration of plasma at steady state
3
Q
Half life (t1/2)
A
t1/2 = (ln[2] x Vd)/ CL
Vd = volume of distribution
CL = clearance
4
Q
maintenance dose (MD)
A
MD =