Eponymous Syndromes

Question 1

Spinal cord hemisection

Contralateral loss of pain/temp/fine touch Ipsilateral motor loss

Answer 1

Brown Sequard

Question 2

Rheumatoid arthritis Splenomegaly

Neutropenia

Answer 2

Felty’s Syndrome

Question 3

Spinning sensation
Increased volume of endolymph
Unilateral tinnitus, unilateral sensorineural hearing loss

Answer 3

Meniere’s Disease

Question 4

Fluid from knee effusion forms popliteal cyst

Rupture leads to compartment syndrome

Answer 4

Baker’s Cyst

Question 5

Systemic vasculitis associated with HLA- B51
Recurrent oral/genital ulceration
Ocular inflammation

Answer 5

Bechet’s Disease

Question 6

Smoking-related

Inflammation of veins, nerves and middle- sized arteries leads to thrombosis leads to gangrene

Answer 6

Buerger’s Disease

Question 7

Rheumatoid arthritis, pneumoconiosis and lung nodules on CXR

Answer 7

Caplan’s Syndrome

Question 8

Peroneal muscular atrophy
Inherited neuropathy that starts in puberty
Weak legs and foot drop
Inverted champagne bottle appearance

Answer 8

Charcot-Marie-Tooth

Question 9

Late-onset asthma
Eosinophilia
Granulomatous small vessel vasculitis P-ANCA +ve

Answer 9

Churg-Strauss Syndrome

Question 10

“Mad cow disease” = prion Spongiform changes

Answer 10

CJD

Question 11

Variant of FAP, 100s of polyps Black spots on fundoscopy

Answer 11

Gardner’s Syndrome

Question 12

Unconjugated hyperbilirubinaemia Jaundice during illness, benign

Answer 12

Gilbert’s Syndrome

Question 13

Pulmonary-renal syndrome

Acute GN + lung symptoms due to anti glomerular basement membrane antibodies

Answer 13

Goodpasteure’s

Question 14

Small vessel vasculitis

Purpura on buttocks + extensor surfaces + GN, joint involvement and abdo pain

Answer 14

Henoch-Schönlein Purpura

Question 15

Ptosis Miosis Anhydrosis

Answer 15

Horner’s Syndrome

Question 16

Decreased EC microfibril formation with poor elastic fibres
Lens dislocation, aortic dissection, long spidery fingers, tall
High arch palate, mitral valve prolapse

Answer 16

Marfan’s Syndrome

Question 17

Contians gastric and pancreatic tissue

Gastric acid secretion à abdo pain and bleeding

Answer 17

Meckel’s Diverticulum

Question 18

Vivid liars, addicted to institution
Feigning illness
By-proxy = injury to dependent person by carer to gain medical attention

Answer 18

Munchausen’s Syndrome

Question 19

Hereditary telangiectasia Epistaxis and GI bleeds

Answer 19

Osler-Weber-Rendu

Question 20

Mucocuntaneous freckles on mucosa/soles/palms

GI polyps à obstruction/bleed

Answer 20

Peutz-Jegher’s Syndrome

Question 21

Penile angulation due to microtrauma during coitus

Answer 21

Peyronie’s Disease

Question 22

“Can’t see, can’t pee, can’t climb a tree” Uveitis, urethritis, arthritis

Answer 22

Reiter’s Syndrome

Question 23

Autoimmune, inflammatory disorder Exocrine gland dysfunction

Xerostomia, keratoconjunctivitis, parotid swelling

Answer 23

Sjorgen’s Syndrome

Question 24

Erythema multiforme

Toxic epidermal necrolysis Hypersensitivity reaction

Answer 24

Stevens-Johnson Syndrome

Question 25

Aortic arch syndrome/pulseless disease Systemic vasculitis leads to dilatation + aneurysm

Answer 25

Takayasu’s Arteritis

Question 26

Bilateral renal cell cancer

Retinal + cerebellar haemangioblastoma Phaeochromocytoma

Answer 26

Von Hippel-Lindau Syndrome

Question 27

Idiopathic costochondritis

Answer 27

Tietze’s Syndrome

Question 28

Lesions to multiple CNS nuclei Post/inf. cerebellar artery occlusion Dysphagia/dysarthria/vertigo/horners

Answer 28

Lateral Medullary Syndrome

Question 29

Ipsilateral 3rd-nerve palse with contralateral hemiplegia Infarction of half of midbrain

Answer 29

Weber’s Syndrome

Question 30

Necrotising granulomatous inflammation Vasculitis of vessels

Upper airway, lung and kidney disease

Answer 30

Wegener’s Granulomatosis

Question 31

GI Malabsorption
Middle-aged white males
Systemic symptoms: arthralgia, GI symptoms, endocarditis, CNS symptoms and hypothalamic syndrome

Answer 31

Whipple’s Disease