EPOC GRAVE Flashcards

1
Q

INHIBIDORES DE LA FOSFODIESTERASA
Roflumilast: MA

A

Inhibe al PD4 → Aumenta la AMPc

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2
Q

INHIBIDORES DE LA FOSFODIESTERASA
Roflumilast: IG

A

EPOC GRAVE

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3
Q

INHIBIDORES DE LA FOSFODIESTERASA
Roflumilast: ADME

A

Sustrato de CYP3A4 y 1A2

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4
Q

INHIBIDORES DE LA FOSFODIESTERASA
Roflumilast: Cual es el Signo caracteristico (EA)

A

DIARREA SEVERA

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5
Q

INHIBIDORES DE LA FOSFODIESTERASA
Roflumilast: Otros Efectos Adversos?

A

Anorexia - Nauseas- Perdida de peso
E. Psiquiatrico (5% px)

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6
Q

Farmacos poco Utilizados por su EA.

A

Mepolizumab - Reslizumab

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7
Q

Estos farmacos ( Mepolizumab y Reslizumab ) pueden generar…? ¿Por qué?

A

Reacción Anafilactica por captura del IgE

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8
Q

Anticuerpos Monoclonales Anti- IgE ¿Cual es el fármaco más Utilizado?

A

Omalizumab

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9
Q

Anticuerpos Monoclonales Anti- IgE
Omalizumab: MA

A

Es un anticuerpo monoclonal Anti-IgE

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10
Q

Anticuerpos Monoclonales Anti- IgE
Omalizumab : Ea ¿reacciones…? ¿Dolor?

A

Aumento de Infecciones
Cefalea, Dolor general y FRACTURAS
>Anorexia

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