EPITHELIAL TX LESSON 5 Flashcards
Covers body surfaces, lin3s body cavities & constitute glands
Epithelium
Composed almost entirely of cells forming a continuous sheet
Cellularity
Containing no blood vessels
Avascular
Supports nerve fibers
Innervated
Epithelial cells are frequently damaged or lost to abrasion so they are replaced quickly
Regeneration
Apical and basak surfaces
Polarity
Protective function
Skin
Secretory function
Glands
Absorptive function
GIT
Sensory function
Tongue and nose
Contractile function
Muscles
Excretory function and maintains e balance
Kidney
Germ cell production
Testes
Epidermis and it’s derivatives (hair, nails, sweat gl, sebaceous gk and mammary gland)
Surface ectoderm
Epith lining the lower urinary tract from the kidneys to the urethra
Transitional epithelium
Simple squamous epith lining the vascular system
Endothelium
Simple squamous epith lining closed cavities of the body
Mesothelium
Directed towards the external surface or the lumen of an enclosed cavity or tube
Apical / free domain
Appears layered through not all of the cells rest in the BM
Pseudostratified Epithelium
Directed
Cytoplasmic processes that extend from the cell surface
Microvilli
Microvilli of unusual length & are immotile
Stereocilia
Motike cytoplasmic structures capable of moving fluid and particles along epithelial surfaces
Cilia (kinocilia)
Much longer than cilia
- In the spermatozoa of humans having 1 flagellum/ tail
- it propels the cell along the female genital tract
Flagella
Communicates w/ adjacent cells and characterized by specialized attachment areas or cell to cell adhesions through junction
Lateral domain
A specialized attachment site on a cell that allowz for support and communication
Cell junction
Directed towards the external surface or the lumen of an enclosed cavity or tube
APICAL/ FREEE domain
8 major functions of epithelial tissue
- Protection
- Sensation
- secretion
- Excretion
- Diffusion
- Absorption
- Contractility
- Transportation
Occluding junctions
Zonula occludens
Tight jx
Anchoring jxns
Zonula adherens
Adhering jxns
Communicating jxns
Gap jxns
Desmosomes
Anchoring jxns
Rests on the basal lamina anchoring the cell to underlying connextive tissue
BASAL domain
No cells but it is a network of a protein fibwrs that connects adjacent epithelial cells
Basement membrane
Reminder: EP TX: RENEWAL AND REPAIR
-Ep cells may only survive for a day or two because they are lost and destroyed.
-replaced by continuous division of unspecialized cells called stem cells
- stem cells are found in deepest layer next to BM
4 cCHON structures of BM
Collagen
Lamines
Entactin
Proteoglycans
BM functions
Structural attachment
Compartmentalization
Filtration
Tissu3 scaffolding
Regulation and signaling
Structural attachment
Anchors epith cells
Compartmentalization
Isolates CT fromt the epith, nerve and muscle cells
Tissue scaffolding
Guide or raised platform for tissue regeneration
Regulation and signaling
Interaction w cell surface receptors
Organized to form the functional component of organs called GLANDS that produce substances that are needed by the body
Glandular epithelium
Secrete their products onto a surface thru epithelial ducts/tubes connexted to a surface
EXOCRINE GLANDS
Here, vesicles fuse w the plasma membrane & extrude their contents by exocytosis
- produxt oozes out of the cell
Merocrine
Part of cell pinches off
Apocrine secretion
Bursts open and dies releasing secretion
Holocrine secretion
Secretory product is released in the apical portion of the cell
- lactating mammary glad
-skin
-eyelid
-ear
Apocrine
Secretory product accumulates w in the maturing cell w undergoes programmed cell death
-sebaceous gl of skin
-meibomian gl of eyelid
Holocrine
Mucoid secretions
-viscous, slimy
Ex: salivary gl and stomach
Mucous gland
Watery secretions
Ex. Parotid gl and pancreas
Serous gland
Lack a duct
Secret their products into the CT
Endocrine glands
Consists of single cells distributed among non secratory cells
Ex. Goblet cell w columnar cells of intestine
Unicellular gland
Consist of >1 cell
Ex. Goblet cells w columnar cells of stomach
Multicellular gland
Classification of ducts
Simple
Compound
Shape of ducts
Tubular
Alveolar
Tubualveolar
Simple
Compound
Tubular
Alveolar
Tubualveolar
Unbranched duct
Branched duct
Tube like
Flask shape
Sac like dilatation