Epithelia Flashcards

1
Q

What are epithelia

A

They form a continuous sheet of cells. They are specialised for distinct functions

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2
Q

What is the function of epithelia

A

They act as barriers between the body and the external world and between fluid compartments within the body. They also transport molecules via absorptive processes

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3
Q

What is simple cuboidal epithelium

A

A single layer of cube cells. Have a central nuclei

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4
Q

What is the function of simple cuboidal epithelium

A

Secretion and absorption

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5
Q

What is the localisation of simple cuboidal epithelium

A

Kidney tubules, ducts, secretory portions of small glands and ovary surface

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6
Q

What is simple columnar epithelium

A

Basal nuclei and ciliated/non ciliated with microvilli

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7
Q

What is the function of simple columnar epithelium

A

Absorption and secretion of mucus and enzymes

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8
Q

What is the localisation of simple columnar epithelium

A

Non ciliated: digestive tract, gallbladder and excretory ducts. Ciliated: small bronchi and uterine tubes

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9
Q

What is simple squamous epithelium

A

Flat cells with disc-shaped nuclei

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10
Q

What is the function of simple squamous epithelium

A

Passage of materials by diffusion and filtration. Secretion of lubricating substances

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11
Q

What is the localisation of simple squamous epithelium

A

Kidney glomeruli, alveoli of lungs and blood vessels

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12
Q

What is simple pseudostratified epithelium

A

They look like there are multiple layers but all cells are in contact with the extracellular matrix. Several layers of nuclei. It is ciliated and non-ciliated

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13
Q

What is the function of simple pseudostratified epithelium

A

Secretion of mucus

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14
Q

What is the localisation of simple pseudostratified epithelium

A

Non ciliated: vas deferens and large glands
Ciliated: trachea and upper respiratory tract

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15
Q

What is stratified cuboidal epithelium

A

Generally 2 layers of cuboidal cells

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16
Q

What is the function of stratified cuboidal epithelium

A

Protects underlying tissue

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17
Q

What is the localisation of stratified cuboidal epithelium

A

Largest ducts of sweat glands and mammary glands

18
Q

What is stratified columnar epithelium

A

Several cell layers. Basal cells usually cuboidal. Superficial cells are elongated and columnar

19
Q

What is the function of stratified columnar epithelium

A

Protection and secretion

20
Q

What is the localisation of stratified columnar epithelium

A

Urethra and conjunctiva of eyes

21
Q

What is transitional epithelium

A

Several cell layers. Resembles stratified squamous and stratified cuboidal epithelium. Basal cells are cuboidal/columnar. Superficial cells are dome-shaped or squamous-like depending on stretch

22
Q

What is the function of transitional epithelium

A

Stretches readily permitting distension of urinary organ

23
Q

What is the localisation of transitional epithelium

A

Ureter, bladder, parts of urethra

24
Q

What is the function of junctional proteins

A

They connect cells to each other and to basement membrane. Some allow intercellular communication eg. transport of ions. Also, enable polarisation

25
Q

What are tight junctions

A

They are the most apical junction. They are a branching network of protein strands

26
Q

What is the function of tight junctions

A

“Zipper” together neighbouring epithelial cells. Defines apical/basolateral boundary. Prevent passage of molecules and ions

27
Q

What are adhering junctions

A

More basal than tight junctions. A “belt” that encircles epithelial cell directly beneath the tight junction

28
Q

What is the function of adhering junctions

A

They allow cell-cell adhesion via interaction between extracellular domain

29
Q

What are desmosomes

A

They are spot like adhesions arranged on the lateral surface of cells

30
Q

What is the function of desmosomes

A

They allow cell-cell adhesion via interaction between extracellular domains

31
Q

What are gap junctions

A

Lateral edges of epithelial cells

32
Q

What is the function of gap junctions

A

Allow intercellular communication

33
Q

What are hemidesmosomes

A

They are localised to the basal surface

34
Q

What is the function of hemidesmosomes

A

They attach epithelial cells to the basement membrane

35
Q

What are microvilli

A

The apical surface area can be increased by presence of a “brush border membrane”

36
Q

What is the function of microvilli

A

They enable absorption

37
Q

What can increase the basolateral surface area

A

Lateral interdigitations and basal foldings

38
Q

What is important about the basolateral surface

A

It is important for transport across the epithelial layer

39
Q

What are cilia

A

They are found on the apical surface of some epithelia. They are larger than microvilli

40
Q

What is the function of cilia

A

They move back and forth to move particles

41
Q

What is stratified squamous epithelium

A

Thick membrane composed of multiple cell layers. Superficial portion of cells are squamous “flattened”. Basal cells are cuboidal/columnar and metabolically active

42
Q

What is the function of stratified squamous epithelium

A

Protects underlying tissue