Epilepsy Management Flashcards

1
Q

What is the first mandatory investigation done to someone who is suspected of having a seizure or a period of syncope?

A

ECG

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2
Q

When is a CT scan indicated over MRI acutely in suspected seizure or syncope?

A
  • Skull fracture
  • Head injury w/ seizure
  • Deteriorating GCS
  • GCS not 15/15 4 hrs after arrival
  • Focal signs
  • Suggestion of other pathology
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3
Q

When is EEG used in epilepsy/seizure/syncope?

A
  • Classification of epilepsy
  • Confirmation of non-epileptic attack
  • Surgical evaluation
  • Conformation of non-convulsive status
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4
Q

How long should a patient not drive for after their first seizure, car & HGV?

A

Car - 6 months
HGV - 5 years

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5
Q

How long should a patient not drive for after a diagnosis of epilepsy, car & HGV?

A

Car - 1 year / 3 years if during sleep
HGV - 10 years of no seizures off medication

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6
Q

How long do epileptic seizures normally last?

A

seconds - minutes

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7
Q

What are the two broad classifications of epileptic seizure?

A

Generalized

Partial - Focal sight of origin

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8
Q

What investigations are used to classify epileptic seizures?

A

Semiology
EEG

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9
Q

Name the types of partial epileptic seizure?

A

Simple - Without impaired consciousness

Complex: with impaired consciousness

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10
Q

What are the different types of generalized epileptic seizure?

A
  • Absence
  • Myoclonic
  • Atonic
  • Tonic
  • Tonic-clonic
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11
Q

What are some key features of generalized epilepsy?

A
  • Genetic predisposition
  • Present in childhood and adolescence
  • Generalized spike-wave abnormality on EEG
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12
Q

What are some key features of partial/focal epilepsy?

A
  • Localized
  • Can generalize laterally
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13
Q

What is the treatment of choice and an alternative for primary generalized epilepsy?

A

Treatment of choice: Sodium valporate

Alternative: Lamotrigine

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14
Q

How does juvenile myoclonic epilepsy present?

A
  • Early morning jerks
  • Generalized seizures

Risk factors: Sleep deprivation & flashing lights

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15
Q

What medication is given for focal onset epilepsy?

A

Carbamazepine or Lamotrigine

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16
Q

What type of epilepsy is associated with hippocampal sclerosis?

A

Frequent focal onset epilepsy

17
Q

What is the mechanism of anti-epileptic drugs?

A

Decrease pre-synaptic excitability
&
Decrease neurotransmitter release

18
Q

What does GABA-A receptor do when responding to GABA?

A

Reduces neuronal excitability

19
Q

What is the 1st line treatment for generalized absence seizure?

A

Ethosuximide

20
Q

What is the 1st line treatment for generalized myoclonic seizure?

A

1st line: Sodium valproate

21
Q

What is the 1st line treatment for generalized Atonic, Tonic & tonic-clonic seizure?

A

Sodium valproate

22
Q

When is phenytoin used in epilepsy/seizure?

A

ONLY in acute management

23
Q

What anti-convulsants should not be used alongside progesterone contraceptives?

A
  • Carbamazepine
  • Oxcarbazepine
  • Phenobarbitol
  • Phenytoin
  • Primidone
  • Topiramate
24
Q

What anti-epileptic medications effect the morning after pill?

A

Enzyme-inducing AED’s