Epilepsy Drugs Flashcards
This drug inhibits neuronal conduction through blockade of neuronal sodium channels. Fast sodium channel inactivation.
Phenytoin (Dilantin)
First line for Focal seizure
This drug inhibits neuronal conduction through blockade of neuronal sodium channels. Fast sodium channel inactivation.
Phenytoin (Dilantin)
First line for Focal seizure
Elevates seizure threshold by decreasing postsynaptic excitation at GABAa receptor.
Phenobarbital (Luminol)
Focal and generalized, except absence
2nd line due to side effects
Elevates seizure threshold by decreasing postsynaptic excitation at GABAa receptor.
Phenobarbital (Luminol)
Focal and generalized, except absence
2nd line due to side effects
Blocks sodium channels during rapid, repetitive, sustained neuronal firing. Fast sodium channel inactivation.
Carbamazepine (Tegretol)
Trigeminal neuralgia
Focal and generalized, except absence
Blocks sodium channels during rapid, repetitive, sustained neuronal firing. Fast sodium channel inactivation.
Carbamazepine (Tegretol)
Trigeminal neuralgia
Focal and generalized, except absence
SIADH can result from chronic use of what drug?
Carbamazepine (Tegretol)
SIADH can result from chronic use of what drug?
Carbamazepine (Tegretol)
Potentiates GABA
Valproic Acid (depakote) 1st line for generalized (myoclonic, atonic, absence)
Potentiates GABA
Valproic Acid (depakote) 1st line for generalized (myoclonic, atonic, absence)
Acute pancreatitis, hepatotoxicity are associated with which drug?
Valproic acid (Depakote)
Acute pancreatitis, hepatotoxicity are associated with which drug?
Valproic acid (Depakote)
Modulated calcium channels, inhibits T-type calcium channels
Ethosuximide
Drug of choice for absence seizures
Modulated calcium channels, inhibits T-type calcium channels
Ethosuximide
Drug of choice for absence seizures
Modulates GABA receptors, blocks NMDA synaptic responses.
Felbamate (Felbatol)
Atonic seizures with LGS
Modulates GABA receptors, blocks NMDA synaptic responses.
Felbamate (Felbatol)
Atonic seizures with LGS
This drug causes aplastic anemia and hepatotoxicity.
Felbamate (Felbatol)
This drug causes aplastic anemia and hepatotoxicity.
Felbamate (Felbatol)
Acts as a unique receptor and inhibits calcium channels.
Gabapentin (Neurontin)
Adj for focal seizure
Acts as a unique receptor and inhibits calcium channels.
Gabapentin (Neurontin)
Adj for focal seizure
This drug is used for chronic pain, peripheral neuropathy and other non-epilepsy conditions.
Gabapentin (Neurontin)
This drug is used for chronic pain, peripheral neuropathy and other non-epilepsy conditions.
Gabapentin (Neurontin)
May block neuronal Na channels. inhibits Ca channels and blocks glutamate release.
Lamotrigine (Lamictal)
Focal seizures
Generalized LGS
May block neuronal Na channels. inhibits Ca channels and blocks glutamate release.
Lamotrigine (Lamictal)
Focal seizures
Generalized LGS
SJS is associated with which drug?
Lamotrigine (lamictal)
SJS is associated with which drug?
Lamotrigine (lamictal)
