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Pharmacotherapeutics > Epilepsy Drugs > Flashcards

Epilepsy Drugs Flashcards

1
Q

This drug inhibits neuronal conduction through blockade of neuronal sodium channels. Fast sodium channel inactivation.

A

Phenytoin (Dilantin)

First line for Focal seizure

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1
Q

This drug inhibits neuronal conduction through blockade of neuronal sodium channels. Fast sodium channel inactivation.

A

Phenytoin (Dilantin)

First line for Focal seizure

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2
Q

Elevates seizure threshold by decreasing postsynaptic excitation at GABAa receptor.

A

Phenobarbital (Luminol)
Focal and generalized, except absence
2nd line due to side effects

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2
Q

Elevates seizure threshold by decreasing postsynaptic excitation at GABAa receptor.

A

Phenobarbital (Luminol)
Focal and generalized, except absence
2nd line due to side effects

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3
Q

Blocks sodium channels during rapid, repetitive, sustained neuronal firing. Fast sodium channel inactivation.

A

Carbamazepine (Tegretol)
Trigeminal neuralgia
Focal and generalized, except absence

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3
Q

Blocks sodium channels during rapid, repetitive, sustained neuronal firing. Fast sodium channel inactivation.

A

Carbamazepine (Tegretol)
Trigeminal neuralgia
Focal and generalized, except absence

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4
Q

SIADH can result from chronic use of what drug?

A

Carbamazepine (Tegretol)

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4
Q

SIADH can result from chronic use of what drug?

A

Carbamazepine (Tegretol)

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5
Q

Potentiates GABA

A 
Valproic Acid (depakote)
1st line for generalized (myoclonic, atonic, absence)
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5
Q

Potentiates GABA

A 
Valproic Acid (depakote)
1st line for generalized (myoclonic, atonic, absence)
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6
Q

Acute pancreatitis, hepatotoxicity are associated with which drug?

A

Valproic acid (Depakote)

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6
Q

Acute pancreatitis, hepatotoxicity are associated with which drug?

A

Valproic acid (Depakote)

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7
Q

Modulated calcium channels, inhibits T-type calcium channels

A

Ethosuximide

Drug of choice for absence seizures

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7
Q

Modulated calcium channels, inhibits T-type calcium channels

A

Ethosuximide

Drug of choice for absence seizures

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8
Q

Modulates GABA receptors, blocks NMDA synaptic responses.

A

Felbamate (Felbatol)

Atonic seizures with LGS

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8
Q

Modulates GABA receptors, blocks NMDA synaptic responses.

A

Felbamate (Felbatol)

Atonic seizures with LGS

9
Q

This drug causes aplastic anemia and hepatotoxicity.

A

Felbamate (Felbatol)

9
Q

This drug causes aplastic anemia and hepatotoxicity.

A

Felbamate (Felbatol)

10
Q

Acts as a unique receptor and inhibits calcium channels.

A

Gabapentin (Neurontin)

Adj for focal seizure

10
Q

Acts as a unique receptor and inhibits calcium channels.

A

Gabapentin (Neurontin)

Adj for focal seizure

11
Q

This drug is used for chronic pain, peripheral neuropathy and other non-epilepsy conditions.

A

Gabapentin (Neurontin)

11
Q

This drug is used for chronic pain, peripheral neuropathy and other non-epilepsy conditions.

A

Gabapentin (Neurontin)

12
Q

May block neuronal Na channels. inhibits Ca channels and blocks glutamate release.

A

Lamotrigine (Lamictal)
Focal seizures
Generalized LGS

12
Q

May block neuronal Na channels. inhibits Ca channels and blocks glutamate release.

A

Lamotrigine (Lamictal)
Focal seizures
Generalized LGS

13
Q

SJS is associated with which drug?

A

Lamotrigine (lamictal)

13
Q

SJS is associated with which drug?

A

Lamotrigine (lamictal)

Pharmacotherapeutics (12 decks)

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