Epilepsy And Tremor Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Features of essential tremor

A
Fine tremor 
Symmetrical 
More prominent on voluntary movement 
Worse when tired, stressed or after caffeine 
Improved by alcohol 
Absent during sleep
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Differentials for tremor

A
Parkinson’s disease 
Multiple sclerosis 
Huntington’s chorea 
Hyperthyroidism 
Fever 
Medication - antipsychotics 
Essential tremor
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Management of essential tremor

A

Propranolol

Primidone - barbiturate anti - epileptic medication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Seizure definition

A

Transient episodes of abnormal electrical activity in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Investigations for epilepsy

A

EEG
MRI brain - tumours
Haematinics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Types of seizures

A
Generalised tonic clinic seizures 
Focal seizures 
Absence seizures 
Atonic seizures 
Myoclonic seizures 
Infantile spasms
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Generalised tonic clonic seizures

A

Loss of consciousness
Tonic - muscle tensing
Clonic - muscle jerking

Tongue biting 
Incontinence 
Groaning 
Irregular breathing 
Post-ictal period
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Post ictal period

A

Time after the seizure where the person is confused, drowsy and feels irritable or depressed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

History of seizure

A

Before, during after
SOCRATES - onset, character, relieving factors, aggravating factors, time and duration

Symptoms:

  • tongue biting
  • incontinence
  • loss of consciousness
  • fever
  • de ja vu
  • hallucinations
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Management of tonic clonic seizures

A

First line - sodium valproate

Second line - lamotrigine or carbamazepine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Focal seizures

A

Start in the temporal lobe, affecting hearing, speech, memory and emotions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Focal seizure presentation

A

Hallucinations
De ja vu
Flashbacks
Auto pilot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Management of focal seizures

A

First line: carbamazepine or lamotrigine

Second line: sodium valproate or levetiracetam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Absence seizures features

A

Typically children

Patient becomes blank and stares into space then abruptly returns to normal

Unaware of surroundings and won’t respond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How to initiate an absence seizure

A

Get child to blow tissue paper repeatedly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Management of absence seizures

A

Sodium valproate

Or ethosuximide

17
Q

Atonic seizures features

A

Drop attacks - brief lapses in muscle tone

Less than 3 minute episodes

18
Q

Which condition is atonic seizures associated with?

A

Lennox- Gastaut syndrome

19
Q

Management of atonic seizures

A

First line: sodium valproate

Second line: lamotrigine

20
Q

Features of myoclonic seizures

A

Sudden brief muscle contractions like a sudden jump

Usually awake

Normally in children as juvenile myoclonic epilepsy

21
Q

Treatment of myoclonic seizures

A

First line: sodium valproate

Second line: lamotrigine, levetiracetam or topiramate

22
Q

Infantile spasm features

A

West syndrome - clusters of full body spasms

Poor prognosis

23
Q

Treatment of West syndrome

A

Prednisolone

Vigabatrin

24
Q

Sodium valproate

A

GABA agonist

25
Q

Side effects of sodium valproate

A

Teratogenic
Liver damage and hepatitis
Hair loss
Tremor

26
Q

Side effects of carbamazepine

A

Agranulocytosis
Aplastic anaemia
Induces P450

27
Q

Phenytoin side effects

A

Folate and vitamin D deficiency
Megaloblastic anaemia
Osteomalacia

28
Q

Ethosuximide side effects

A

Night terrors

Rashes

29
Q

Lamotrigine side effects

A

Steven Johnson’s syndrome

Leukopenia

30
Q

When to admit a seizure

A

Lasting more than 5 minutes ore more than 3 seizures in 1 hour

31
Q

Status epilepticus

A

When seizure persists for > 5 mins

Medical emergency

32
Q

Status Epilepticus management

A

A-E

  • secure airway
  • high concentration oxygen 15L
  • check blood glucose levels
  • IV lorazepam 4mg repeated after 10 minutes if seizure continues
  • if persists - phenobarbital or phenytoin
33
Q

Medications in the community for status epilepticus

A

Buccal Midazolam

Rectal diazepam