Epilepsy Flashcards

1
Q

What is epilepsy?

A

Epilepsy is a condition associated with reduced GABA levels in the brain that leads to abnormal cell-cell message propagation

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2
Q

What are the signs and symptoms of a febrile seizure?

A
  • fever
  • face may turn blue or red
  • eyes rolling upwards
  • loss of consciousness
  • muscles and limbs jerk
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3
Q

At what temperature are patients more at risk of a seizure?

A

above 38 degrees

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4
Q

What are the main classifications of epilepsy?

A
  • Generalised
  • Partial
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5
Q

What are the divisions of generalised epilepsy?

A
  • tonic/clonic
  • absence
  • myclonic/atonic
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6
Q

What are the divisions of partial epilepsy?

A
  • simple partial
  • complex partial
  • simple sensory
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7
Q

What are the triggers for epilepsy?

A
  • idiopathic
  • trauma (head injury)
  • CNS disease
  • social
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8
Q

what are examples of CNS diseases that can trigger epilepsy?

A
  • tumour
  • stroke
  • CJD
  • meningitis
  • encephalitis
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9
Q

what are examples of social triggers for epilepsy?

A
  • late nights
  • alcohol
  • hypoglycaemia
  • flashing lights
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10
Q

What are the features of Tonic Clonic seizures?

A
  • prodromal aura
  • loss of consciousness/continence
  • initial tonic
  • clonic phase
  • post-ictal drowsiness
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11
Q

what does tonic mean in relation to seizures?

A

Body becomes extremely stiff
- can be dangerous to spine

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12
Q

what does clonic mean in relation to seizures?

A

Contraction/relaxation of body
- jerky movements at this point

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13
Q

how long do tonic clonic seizures typically last for?

A

1-3mins
- can be recurrent however and this is dangerous

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14
Q

Why are status epilepticus (recurrent seizures) so dangerous?

A

Patient becomes increasingly hypoxic which can affect the brain

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15
Q

What are the features of Petit Mal (absence) seizures?

A
  • short lived episodes (5-15 seconds)
  • loss of awareness
  • eyelids flutter, vacant stare, stops activity, loss of response
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16
Q

How do tonic-clonic seizures affect the medical status of a patient?

A

INJURY prone
- may fall & get hurt
- must remove objects from mouth

Asphyxia
- use supplemental oxygen
- suction any secretions

17
Q

What epilepsy medication can affect pregnancy?

A

Sodium Valproate
- if taken during pregnancy it can significantly damage baby

18
Q

what are some precipitators for tonic-clonic seizures?

A
  • poor medication compliance
  • GA agents
  • alcohol
  • tricyclics & SSRIs (antidepressants)
  • fatigue/stress
  • infection
  • menstruation
19
Q

What are partial seizures?

A

Seizures that are localised to ONE region of the brain
- may move/spread to other ares

20
Q

What preventative treatment is used for epilepsy patients?

A

Anticonvulsant drugs
- carbamazepine
- gabapentin
- phenytoin
- valproate

21
Q

What emergency treatment is used for epilepsy patients?

A
  • airway & oxygen
  • status epilepticus requires BENZODIAZEPINES
22
Q

how do epilepsy drugs work?

A

Act on either:
- GABA receptor actions
- sodium channel actions

23
Q

what are examples of GABA receptor epilepsy drugs?

A
  • valproate
  • benzodiazepine
24
Q

what are examples of sodium channel acting epilepsy drugs?

A
  • carbamazepine
  • phenytoin
25
Q

how does valproate work?

A

GABA transaminase inhibitor

26
Q

how do benzodiazepines work?

A

GABAa receptor action on Cl enhanced

27
Q

How does epilepsy affect dentistry?

A

Complications of fits
- oral soft tissue injury
- dental injury/fracture

Complication of treatment
- gingival hyperplasia
- bleeding tendency
- folate deficiency

28
Q

what epilepsy drug can cause gingival hyperplasia?

A

phenytoin

29
Q

what epilepsy drug can increase bleeding tendency?

A

valproate

30
Q

An epileptic patient comes into your practise requiring treatment, how would you know it is safe to do so?

A
  • ask when last three fits took place
  • ask about compliance with medication
  • ask about any changes in medication