Epidermis Flashcards
histology
study of the structure and composition of skin tissue
physiology
studly of the function of skin tissue
6 primary functions
protection, absortion, secretion,sensation, excretion, and regulation of temp.
how does the skin protect us?
-melanin-from UV radiation
-acid mantle-protects against bacteria and TEWL
is slightly acidic (5.5-5.6)
What is the acid mantle made up of?
sebum, sweat (lactic acid), water and keratohyalin
how does the skin regulate temperature?
- perspiration/evaporation to cool the body,
- arrector pili muscles cause goose bumps to trap warmth in.
stratum germinativum
- AKA basal layer
- 1 layer
- 70-90% water
- Mitotic
- held together by desmosomes (cell process)
- melanocytes every 10-15 cells (skin color)
stratum spinosum
- AKA spiney layer
- 5-8 layers
- 60-70% water
- Keratin production for strength and protection
- Langerhans immune cells to detect and process foreign antigens
stratum granulosum
- AKA grainy layer
- 3-5 layers
- 20-60% water
- transitional layer between living and dead cells
- Keratohyalin- an intercellular lipid glue that replaces the desmosomes
- Membrane Coating Granules- make cell 6X stronger
stratum lucidum
- AKA clear layer
- 3-5 layers
- 10-20% water
- epidermal ridges that form our fingerprints
- thickest on palms and soles
stratum corneum
- AKA horny layer
- 15-20 layers
- 5-10% water
- desquamation occurs which is the skin natural shedding process
keratinization process
the 28 day upward migration of skin cells from the stratum germinativum to the stratum corneum
basement membrane
- AKA dermo-epidermal junction
- separates the epidermis and dermis
- transports nutrients from the vascular dermis to the -avascular epidermis.
melanin
pigment produced by the malanocyte to give us our skin color
melanogenesis
-process by which melanin is produced
-the melanosome (an organelle) is stimulated
-It uses tyrosine (amino acid) and tyrosinase (enzyme)
to produce melanin
-melanin is produced and transported from the melanocyte to the surrounding cells