Epidemiology/Prevalence

Question 1

Delerium Prevalence in Hospital

Answer 1

• 10-20% of medical/surgical inpatients

Question 2

Alzheimer’s Genetics

Answer 2

• Familial autosomal dominant early onset - 1% of cases
• Else if 1st degree relative affected risk increase 3-3.5x (1/5-6 will develop)
• Chromosomes
  
  • APoE4 X21
  • Presenelin 1 X14
  • Presenelin 2 X1

Question 3

Mild Cognitive Impairment Incidence and Rate of Progression to Dementia

Answer 3

• 15% of normally ageing individuals get MCI
• 5-10% of MCI cases per year go on to develop dementia

Question 4

ADHD genetic risk

Answer 4

• If sibling affected then 2-3x increased risk
• Other risk factors:
  
  • Low birth weight
  • Maternal drug/EtOH use
  • Head injury

Question 5

Schizophenia Prognosis

Answer 5

• 1/5 no recurrence
• 3/5 relapsing-remitting picture
• 1/5 never recover

Question 6

Schizophrenia - Antipsychotic Efficacy %

Answer 6

• 80% of patients respond to antipsychotics

Question 7

Schizophrenia - Genetic Risks

Answer 7

• General population 1%
• Full sibling affected 9%
• Parent affected 13%

Question 8

Alzheimers Prevalence

Answer 8

• 5-7% of all >60s

Question 9

Anorexia - Genetics

Answer 9

• In female siblings of affected 6-10% risk

Question 10

Bipolar Affective Disorder - Genetic Risk

Answer 10

• 1st degree relative of affected - 5-10% risk (some estimates higher)

Question 11

Post MI Depression - Prevalence and Impact on Mortality

Answer 11

• 20% prevalence
• Increases mortality by 2-6x

Question 12

Postnatal Psychosis - Incidence and Risk of Recurrence

Answer 12

• Incidence 1-2/1000 live births
• Recurrence risk 30-80% in future pregnancies

Question 13

Postnatal Depression - Incidence for: General Population, History of Depression, History of PND

Answer 13

• General population 10-15% within 6 months, peak at 3-4 weeks
• History of depression 25%
• History of postnatal depression 50%