Epidemiology/ Biostatistics II Flashcards
What is late look bias?
Information gathered at an inappropriate time (ex. Using a survey to study a fatal disease- only alive patients respond) (p.53)
What is lead time bias?
Early detection confused with increased survival (p.53)
What is observer-expectancy effect?
Occurs when a researcher’s belief in the efficacy of a treatment changes the outcome of that treatment (p.53)
What is the Hawthorne Effect?
Occurs when the group being studied changes its behaviour owing to knowledge of being studied (p.53)
How does sample size effect Standard Error of the Mean?
SEM decreases as sample size increases (p.54)
What is type I error and how is it measured?
Stating that there is a difference when none exists; mistakenly accepting the alternative hypothesis and rejecting the null). Measured as alpha level, or P value; false positive error (p.54)
What is type II error and how is it measured?
Stating there is not an effect or difference when one exists; failure to reject the null hypothesis when it is in fact false. Measured by beta; false negative error (p.54)
What is power of a study and how is it measured?
(1-beta) is the probability of rejecting the null hypothesis when it is false or the liklihood of finding a difference if one exists. (p.55)
Name three ways to increase the power of a study.
increase sample size, increase expected effect size, increase precision of measurement (p.55)
What type of study has the highest power?
A meta-analysis study (p.55)
How is a confidence interval measured?
CI = range from (mean-Z(SEM)) to (mean + Z(SEM)) (p.55)
What is implied if a confidence interval for a mean difference between two variables includes zero?
There is no significant difference and H0 is not rejected (p.55)
What is implied if a confidence interval for an odds ratio or relative risk includes the number one?
H0 is not rejected (p.55)
What is measured by a t-test?
Difference between the MEANS of two groups (p.55)
What is measured by an ANOVA test?
Difference between the MEANS of three or more groups (p.55)