Epidemiology Flashcards

1
Q

Epidemiologic Triad

A

Agent&raquo_space;Host&raquo_space;Environment (sometimes vector in middle)

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2
Q

Host factors

A

Degree to which individuals adapt to stressors produced by the agent (genotype, nutrition, immune system, behavior, BMI)

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3
Q

Agents of disease

A

Biologic (virus, bacteria, etc), chemical, physical, social

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4
Q

Environment

A

Probability and circumstances of exposure of host to agent

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5
Q

Vectors

A

Insects, arthropods, animals (must have specific relationship with agent, host, and environment)

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6
Q

Endemic

A

Constant presence of disease in specific geographic area

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7
Q

Epidemic

A

Outbreak of a disease affecting many people in a specific region

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8
Q

Pandemic

A

Worldwide epidemic

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9
Q

Iatrogenic

A

Symptom or disease caused by medical treatment

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10
Q

Natural history of disease

A

Normal»Preclinical phase (after biologic onset of disease)»Clinical phase (symptoms first appear»disease diagnosed»therapy given)

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11
Q

Primary prevention

A

Preventing the initial development of disease (immunization, smoking cessation)

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12
Q

Secondary prevention

A

Early detection in the preclinical phase to slow/prevent progression or reduce complications (screening for cancer or prediabetes)

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13
Q

Tertiary prevention

A

Reducing impact of disease or comorbidities (diabetic foot checks, stroke rehab)

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14
Q

Prevalence

A

Proportion of population with disease (# of existing cases at a given time point/total population at risk)

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15
Q

Incidence

A

proportion of population developing new cases of disease (# of newly diagnosed cases during a time period/total population at risk)

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16
Q

Annual mortality rate (all cause)

A

(# of deaths in 1 year/# of people in population at midyear)*1000

17
Q

Case-fatality rate

A

Percentage of deaths among patients with the disease (# of individuals dying during a specific time frame after diagnosis/# of individuals with the disease)*100

18
Q

Epidemiology studies can be either…or….

A

Observational; experimental

19
Q

Observational studies

A

Descriptive, ecological, cross-sectional, case-control, cohort

20
Q

Experimental studies

A

Randomized clinical trials (RCTs)

21
Q

Hierarchy of evidence

A

Lab research»case series/reports/case-control studies»cohort studies»RCT»systematic review»meta-analysis