Epibulbar

Question 1

conj naevus - sign of potential malignancy

Answer 1

palpebral or forniceal, prominent feeder vessels, sudden growth or increase in pigmentation, development after second decade

Question 2

conj papilloma - treatment

Answer 2

excision, cryotherapy, subconj interferon alfa, carbon dioxide laser vaporization, topical mitomycin C, cimetidine

Question 3

Limbal dermoid - where, syndromes

Answer 3

inferotemp. limbus, Goldenhar, Treacher Collins, Linear naevus sebaceus of Jadasohn

Question 4

Goldenhar syndrome

Answer 4

mr, epibulbar dermoid, upper eyelid coloboma, preauricular skin tags, vertebral anomalies, hypoplasia maxilla mandibula

Question 5

linear nevus sebaceous syndrome

Answer 5

lipodermoids (or dermolipomas), Complex choristomas

Question 6

Goldenhar syndrome name

Answer 6

oculoauriculovertebral dysgenesis

Question 7

Treatment for PAM

Answer 7

excision with cryotherapy

Question 8

Lesar-Trelat sign

Answer 8

sudden onset of numerous seborrheic keratoses –> work-up for gastrointestinal adenocarcinoma

Question 9

PAM - uni or bi, in whom

Answer 9

uni, light-colored, middle-age

Question 10

PAM - % progress to conj melanoma

Answer 10

30-50%

Question 11

PAM - location suspicious for atypia

Answer 11

palpebral, fornix, plica, caruncule

Question 12

Benign melanosis - where

Answer 12

perilimbal conj, may extend onto the peripheral cornea (“striate melanokeratosis”)

Question 13

Nevus of Ota

Answer 13

oculodermal melanocytosis

Question 14

Risk of melanoma in Risk of melanoma in ocular or oculodermal melanocytosis

Answer 14

1/400

Question 15

Risk of glaucoma in ocular or oculodermal melanocytosis

Answer 15

10%

Question 16

% of conj melanoma arise from PAM

Answer 16

70%

Question 17

Factors with risk of PAM progression

Answer 17

more than 3 hour clocks of pigmentation, caruncule, fornix, palpebral

Question 18

Conj melanoma - recurrence rate

Answer 18

50%

Question 19

Origin of conj melanoma

Answer 19

70% PAM, 25% de novo, 5% nevus

Question 20

Melanoma - poor prognosis

Answer 20

palpebral, fornix, caruncule, eyelid margin. tchickness >1.8mm, pagetoid, full-thickness intraepithelial spread, lymphatic invasion, mixed cell type, de novo, not limbus, residual involvement at the surgical margin

Question 21

Margin in excision of nevus

Answer 21

2mm

Question 22

Reddish brown nodule on the surface on the caruncule

Answer 22

onkocytoma

Question 23

slow-growing cystadenoma

Answer 23

onkocytoma

Question 24

onkocytoma cystadenoma - origin

Answer 24

ductal and acinar cells of main and accessory lacrimal glands

Question 25

Treatment of CIN

Answer 25

excision with 3-4 mm margins and cryotherapy, topical IF2b, MMC, 5-FU

Question 26

Ataxia-Telangiectasia

Answer 26

AR, Louis-Barr syndrome, can’t initiate saccades, carriers - risk of breast cancer