A

Question 1

Retinal astrocytic hamartoma / Retinal astrocytoma - in which diseases

Answer 1

Tuberous sclerosis (Bourneville disease), NF1, retinitis pigmentosa

Question 2

Tuberous sclerosis (Bourneville disease)

Answer 2

60% sporadic, triad-epilepsy,mr,adenoma sebaceum, Ash leaf spots, Shagreen patches, skin tags, cafe-au-lait, subependymal astrocytic, giant cell astro., renal angiomyolipoma, cardiac rhabdomyoma, pulmonary lymphangioma, patchy iris hypopigmentation, atypical iris colobomas

Question 3

Acquired retinal astrocytoma

Answer 3

old, solitary, growth, sRD, lipid exudation

Question 4

Capillary hemangioma (hemangioblastoma)

Answer 4

VHL, capillary-like channels, foamy stromal cells, growth, exudation (+remote) , young, anterior

Question 5

VHL

Answer 5

80%AD, Capillary hemangioma, CNS hemangioma, pheochromocytoma, renal pancreatic carcinoma, cysts

Question 6

Vasoproliferative tumor

Answer 6

ant to equator, inferotemp, exu, hemor, sRD, secondary-int uveitis, trauma, pigmentosa, chronic RD,

Question 7

Cavernous hemangioma

Answer 7

sporadic, Oculoneurocutaneus syndrome (AD, CNS cutaneus angiomas), no exud, grapes, FA sedimentation, no photocoagulation

Question 8

Racemose hemangioma

Answer 8

uni, asymptomatic, Wyburn-Mason syndrome (non-hereditary, cutaneous CNS hemangioma)

Question 9

Combined hamartoma of Retina and RPE

Answer 9

uni, associations: none, NF2, Gorlin, brachio-oculofacial s., incontinentia pigmenti, x-linked retinoschisis

Question 10

Adenoma of RPE

Answer 10

vitreous inflammatory cells, exud, feeding artery and vein

Question 11

Atypical congenital hypertrophy of the RPE

Answer 11

Familial adenomatous polyposis, Gardner syndrome (FAP, osteoma skull mandible and long bones, epidermoid cysts, lipomas, fibromas), Turcot s. (AD or AR, FAP, medulloblastoma, glioma)

Question 12

Melanocytoma - cells

Answer 12

large polyhedral or spindle cells

Question 13

Touton giant cells and large foamy histiocytes

Answer 13

Juvenile Xanthogranuloma

Question 14

Melanoma mnemonic

Answer 14

Thickness greater than 2mm, Fluid, Symptoms, Orange , Margin within 3 mm, Ultrasonographic Hollowness, Halo absent, Drusen absent

Question 15

Which gene mutation is associated with best prognosis in uveal melanoma

Answer 15

EIF1AX, SF3B1

Question 16

Which gene mutation is associated with META in uveal melanoma

Answer 16

class 2 gene expression profile (GEP), BAP1

Question 17

What procedure is contraindicated in uveal melanoma

Answer 17

diathermy

Question 18

Most common intraocular tumor overall

Answer 18

metastases

Question 19

CAR - antibodies

Answer 19

anti-recoverin antibodies

Question 20

Type of non-Langerhans’ cell histiocytosis

Answer 20

Juvenile Xanthogranuloma