Epi Exam 2 Flashcards
HACCP is required for what facilities?
- Meat
- Seafood
- Juice
Applies to almost any step in the production chain “farm to fork”
Which gram neg. seafood pathogen is most common and is transmitted to humans by ingestion of improperly cooked seafood/oysters and by direct skin contant with infected water?
Vibrio vulnificus + parahaemolyticus
What is the CAC?
Codex Alimentarius Commission (CAC)
- Intergovernmental body that coordinates food standards at the international level
- Main objectives are to protect the health of consumers and ensure fair practices in food trade
- Used by governments to determine and refine policies and programs under their national food control system
How are humans infected by WNV?
Primarily through the bite of infected mosquitoes.
Also through blood, lab exposure and breast milk.
there is NO EVIDENCE of humans being infected through handling dead/ill birds
What is the most common cause of foodborne illness?
Norovirus
What is most important way to prevent norovirus infection?
Proper preparation, cooking and handling of food
Also sanitation, water treatment, personal hygiene
Bites from __________ animals NEVER pose a rabies threat
non-mammalian
T/F: TB reactors cannot be slaughtered for any form of human consumption due to the risk of zoonosis.
False
TB reactors are considered “suspect” and have a extra postmortem inspection.
Once TB infected tissue is removed, the remainder of the carcass may be only passed for human food that is COOKED
Norovirus infections provide _____ cross protection to other strains
poor
T/F: people believe that nutrients are lost by pasteurization and that pasteurization causes milk allergies….
true…
What is the case definition of Hep A?
- CS/ jaundice/elevated serum aminotransferase
AND
- Positive IgM or epidemiological link to confirmed case
What should you do if your poultry meat is contaminated?
trim and wash with chlorinated water if possible; otherwise, condemn
What foodborne bacterial infection cause hemolytic uremic syndrome?
STEC E.coli O157:H7
These are all things that the _______ Meat Inspection does
- Ensure that food products are free of foodborne pathogens
- Antemortem & Postmortem inspection
- HACCP and risk based approaches to reducing pathogens
- Clearly label foods that pass inspection
- Minimize contamination during processing
- Monitor for drug residues and pathogens
Federal
Rickettsia felis can maybe cause ________-like illness in humans and survives in a cat-flea cycle.
typhus
What inherited syndrome in pigs is characterized by malignant hyperthermia in response to stress that affects survival and meat quality?
Porcine Stress Syndrome (PSS)
What are the 5 National Food Control Components?
- *1. Food Law and Regulations**
- *2. Food Control Management-** consist mostly of USDA and FDA
- *3. Inspection Services- USDA-FSIS & FDA (80%)**
- *4. Laboratory Services:** Food Monitoring and Epidemiological Data- USDA & FDA
- *5. Information, Education, Communication and Training**
Rocky Mounted Spotted Fever (Richettsia rickettsii) is transmitted by __________________ in the USA
BOTH species of Dermacentor
What are some examples of corrective actions that could be taken if a cooking temperature is not met in a HACCP facility?
- Check that the thermometer is working (he repeated this ALOT)
- Pull the batch until the problem is resolved
- Repeat the cooking step
T/F: TB positive animals can be passed with restrictions if the lesions are localized, ecapsulated/calcified and trimmed from the carcass
True
What is unique about the intoxication by C. perfringens?
Toxins form in the GI tract, not in the food prior to ingestion
In the USA, do abattoirs monitor for Trichinella spiralis
Nope, they assume consumers are educated and know to cook meat
Ixodes ticks must be attached for > ____ hours to transmit lyme disease
>48 hours
Persons _____years of age have the highest risk of presenting with severe WNV symptoms
>50 years
_______
1/150 people get neuroinvasive signs
20% of people have mild febrile illness
80% of humans are asymptomatic
Animal suspected of having diseases or conditions that would make part or all of the carcass unfit for food that need a detailed postmortem inspection are considered _____ animals
Suspect
Can “Downer Cattle” be slaughtered?
Nope, they have a higher probability of being infected with BSE prions
What does it mean for a meat to be adulterated?
Including an added, foreign or interior substance, that cannot be removed by trimming
What is the best way to reduce meat-associated parasitic diseases?
Cook meat thoroughly!
Also:
- Avoid food animal exposure
- Meat inspection
- Freezing (some parasites)
- Hygeine
What is the main causative agent of Cat scratch disease?
**Bartonella henselae**
When clinical signs are present in an animal at the slaughter house, what generality determines if the animal is “suspect” vs “condemned”?
Suspect- signs indicate a localized disease
Condemned- signs indicate a generalized disease
What are SRM? What do they include at all ages? and if >30 months?
**** IMPORTANT****
SRM = specific risk matrial that are defined as “inedible” based upon risk of BSE transmission to human
All ages: tonsils and distal ilium
>30 months: brain, skull, eyes, terminal ganglia, spinal cord, vertenral column, dorsal root ganglia
Define Food Control
Mandatory regulatory activity of enforcement by national or local authorities to provide consumer protection, wholesomeness, safety, quality and accuratly labeled products.
T/F: Raw milk sale is legal in the USA
False! It is illegal in some states. Some “Cow-shares” can bypass the law if milk is used for own consumption.
What obligate parasitic protozoa, that are vectored by insects, infect dogs in the USA?
Leishmania infantum and T. cruzi (Chagas disease)
What causes 30% of chronically infected humans to develop heart disease and 10% of chronically ill humans to develop megaesophagus/colon?
Trypanosoma cruzi in southern AMERICA
spillover hosts (humans, equids, cattle) of rabies have _______ transmission
inefficient
but still possible
Which tapeworm causes minor bloating & anemia after ingestion of raw infected fresh water or anadromous fish: Ceviche, sushi, pickled herring? how is it prevented?
Diphyllobothrium latum
prevent via cooking or freezing fish at appropriate temp and time
T/F: WEEV is rare in humans and equids and causes similar clinical signs to EEEV, but are less severe/common
true
In EEEV, _______ cases often appear ~ 2weeks before humans
equine
______
Begin with fever, lack of appetite and lethargy
– Progresses to various degrees of excitability and then drowsiness, ultimately ending in paresis, seizures and coma in fatal cases (5-‐10 day course)
Babesia’s life cycle is between which two hosts?
Small rodents and ticks (Ixodes spp.)
Other species, such as dogs, can contract the disease and have a hemolytic anemia.
How do humans become infested wth Cuterebra?
Broken skin, intact skin, and mucous membranes
____
uncommon in humans
enzootic in USA and southeast canada in dogs, cats and rabbits
What pathogen is the second largest cause of death from boodborne dz in the US?
Toxoplasma gondii - cause issues in healthy, immunocompromised and pregnent women
What diseases do Ixodes ticks transmit? What is their distributionin the USA?
(1) Borrelia burgdorferi - lyme disease
(2) Anaplasma phagocytophilum - similar to lyme
(3) Babesia- hemolytic anemia
See map for distribution. All of these disease are increasing
Does the AVMA support breed bans to prevent biting?
NOPE
Animals are considered immunized ____ days after their first rabies vaccine
28
Critical limitsfor each CCP must be able to be _____
measured (ie. temp, time)
How do you prevent/control mosquito borne-disease?
Larvae control
Source Reduction (reduce standing water)
Adulticide
Public Education
How are humans and livestock infected with T. gondii?
People: (1) eating oocytes in litter soil, contaminated food/water (2) Eating bradyzoite in undercooked meat (3) Vertical
Livestock: (1) eating oocyst (2) eating bradyzoite in rodents, birds and other animals (food contamination)
These 4 roles are part of what veterinary service agency?
- Management- policy development, risk assesment, auditing
- On Farm Food Safety Programs- health and hygeine
- Meat Inspection Programs- direct inspection, supervision, HACCP
- Certification of products for international trade
USDA-FSIS
What are the regulations of seafood?
** Learning objective**
- FDA- limited, gives “warning”
- HACCP is required for all USA seafood plants
- Dept. of Commerce (NOAA) - voluntary seafood inspection program
- Pulblic Health services - can close waters
How is swine cysticercosis prevented?
Target vehicle (treat and educate humans) & human sewage management
What are the enzootic and epizootic reservoir hosts of VEEV?
enzootic: rodents
epizootic: horses
Mosquitoes are biological vectors
Canine rabies may be eliminated by ________
mass dog vaccination!
Define Food Safety
prevent hazards from entering and remove/reduce hazard from the food chain to ensure food safety.
Consist of pre-harvest and post-harvest components.
Which intoxication bacteria is associated with improper canning of food?
Clostridium botulinum
In what species is electricity used for stunning of animals? What happes if there is excessive amps?
Calves, sheep, goats, swine, cattle (rare)
excessive amps –> petechial hemorrhages –> condemned
What is a typical mosquito life cycle?
E-L-P-A
Reservoir hosts (Carnivora and Chiroptera) of rabies have _______ interspecies transmission/maintenance
sustained
Why are there no human cases of Leishmania infantum in the USA?
no vector (sandfly) - it is a TROPICAL disease
Trypanosoma brucei isTransmitted by
bite of ________ flies in Africa
tsetse
_________
causes sleeping sickness in humans and cattle that can last for years and ends in death
T. b. rhodesiense – cattle are primary reservoir; causes fast onset acute trypanosomiasis in humans
These are objective to what process?
- Protect public health
- Consumer confidence
- Surveillance of animal health problems
- Improved access to international export markets
Meat Inspection
___________ is a leading cause of postmortem condemnation due to neoplasia
Epithelioma / Squamous cell carcinoma
What is the difference between the typical symptoms of foodborne intoxication and infection?
-
Intoxication
- rapid onset- 30 mins to hours
- duration - 1-2 days
- Damage enterocytes
- EXCEPTION - botulism toxin= neurotoxin
-
Infection
- onset- several hours to days
- duration- several days
- enterotoxin production –> watery diarrhea
- some kill enterocytes –> dysentery, fever and septicemia
What are the clinical signs of Cat Scratch Disease (Bartonella) in immunocompetent and immunocompromised people?**********
-
Immunocompetent adults = fairly mild disease
- – Fever + lymphadenopathy of draining LN
- – Papule often seen at site of bite/scratch
- – Can last a few months if untreated
-
Immunocompromised people = severe!!!!
- – Bacillary angiomatosis
- – Chronic fever
- – Endocarditis, hepatitis, encephalitis …
T/F: Grade A milk is defined and regulated by Pasteurized Milk Ordinance (PMO). This is revised every other year by at the NCIMS with representatives of the FDA, USDA, State govt, local gov’t, dairy industry and academia
true!
When is carbon dioxide used to stun animals? what species is it used in?
It is used to depopulate pigs and chicken farms
Can also be used in swine, sheep and calves
Animals being boostered for rabies after one year of their initial vaccine are consided immunized ________
immediately
T/F: The pre-exposure rabies vaccine is protective against all species/genotypes of Lyssavirus that cause rabies
FALSE! it is ineffective against several bat and foreign rabies viruses.
What are the benefits of pasteurization of milk?
Destroys pathogens (Coxiella burnetii etc.)
Inactivates enzymes in milk (lipase)
Enhances shelf life
Where is Amblyomma americanum located? What zoonotic diseases does it transmit?
Transmits:
(1) Ehrlichia chaffeensis & E. eqingii - infecrs humans and dogs
(2) Panola Mt. Ehrlichia- infects humans and goats
(3) Tularemia/Francisella tularensis -infects rabbits and humans
What dermatophytosis is most common in the developed world? Which animals spread it to people?
Microsporum canis
Usually spreads form cats (asymptomatic carriers) to dogs and to humans
-
These are all _______inspection legands
USDA
What is the reservoir of Bacillus cereus? What are the two clinical presentations?
SOIL!
Enteric Form (vomiting) and Diarrhea form
Untreated, infected ______ can serve as “domestic sources of infected ticks
dogs
How do humans and animals develop cysticercosis?
Ingestion of human (DH) feces!
People get this by consuming tape worm eggs (T solium only)
Cattle, sheep, pigs get cysticercosis by consuming tapeworm eggs from human feces
What makes up 59% of veterinarian and vet staff workmans comp claims?
bite wounds
Which nematode causes tingling in throat, coughing up worms, acute abdominal pain (mimic appendicitis, crohns and stomach cancer) that is acquied by ingestin crustaceans, fish or squid worldwide?
Anisakis spp.
What virus is the most common cause of severe diarrhea in children around the world?
Rotavirus
+++ in winter
After exposure, Wild mammalian carnivores or bats that are not available or suitable for testing for rabies should be regarded as ____ animals
rabid
What should you do if a rabies vaccinated dog/cat/ferret bites a human?
Quarantine animal for 10 days with daily exams, have a veterinarian exam the animal at beginning and end of quarantine
If symptomatic= euthanize & test
How are humans infected with Cat Scratch Disease (Bartonella)?
bitten or scratched by an infected cats
What are signs of a effective captive bolt/gun shot stun?
- Animal immediately collapses
- Becomes rigid with forelimbs extended for 10-‐20 seconds followed by involuntary kicking movements then relaxation
- Eyes will be central and fixed
- No corneal reflex
- No rhythmic breathing
- Heart beat will continue for some time
What food does the USDA regulate?
Meat, poultry
catfish
egg products
imported shell eggs
What causes a self-limiting superficial fungal skin infection in humans that is transmitted by direct contact and through spores on fomites with abraded skin?
Dermatophytosis (“Ringworm”)
_____________
introduced into abraded skin
requires a strong CMI response to recover
Microsporum canis is most common in the developed world
What are the two groups of zoonotic diseases that Borellia causes & what are their vectors?
–Lyme disease type = Ixodes spp. hard ticks
–Relapsing fever type = soft ticks
______________________ causes mild rashes (compared to sarcoptes) in humans. Although humans are highly susceptible, this pruritic rash usually stops once the animal is treated.
Cheyletiella spp. - Walking dandruff
T/F: only some dogs, cats, ferrets and horses should be vaccinated for rabies
False! All should be legally vaccinated
only some livestock (valuable, in contact with people) should be vaccinated
True or False
Mites and Ticks are Insects
FALSE
Insects = 6 legs
Mites/Ticks (Acari)= 8 legs
Rabies virus is present in saliva late in infections is usally transmitted to susceptible host by _______
bite wounds
How do humans get taeniasis?
Eating undercooked meat with tapeworm cycst
———-
Develop adult stage tapeworms within the intestinal tract
What is the most common pathogen in dog bites?
Pasteurella
____
(only 3-18% of wounds get infected)
Others: Streptococcus, Staphylococcus, Moraxella, Corynebacterium, Neisseria
What are 4 poultry-specific diseases that lead to a carcass being condemned?
- Chlamydia psittaci (chlamydiosis, etc.) – Zoonotic! lung congestion, cardiac enlargement, fibrinous exudates
- Mycobacterium avium (“TB”)
- Leukosis complex (incl. Marek’s)
- Airsacculitis – condemn if extensive
What three groups are most likely to be bitten by a dog?
children > elderly > postal service workers
Meat can be Passed with_______ when the zoonotic risk is minor and can be mitigated by cooking, freezing, etc.
Restrictions
All species with rabies present with paralysis of the muscles in the ______ which may present as dysphagia, salivation, “hydrophobia” and may resemble “choke” in cattle
throat
Pasteurization if a function of ____ and _____
time and temperature
What factors determine the incubation period of rabies?
Number of viruses innoculated
vacinity to the head
innervation
When do you trim? when do you condemn?
Trim = localized
Condemn= generalized, zoonotic, unappealing
What is the main reservoir of Bartonella henselae?
Cats = “Cat Scratch Disease”
Most cats are asymptomatic
Kittens more likely to be shedding bacteria
More common in warm & humid climates from July- October
Rig provides immediate passive immunity to rabies for ___ to ____ days
7-10 days
Most common etiology of mastitis is ___
S. aureus
Also caused by Streptococcus spp., E. coli, Klebsiella,
Mycoplasma spp., Serratia etc
When are children usually bitten by dogs?
when theiris an absence of an able-bodied person to intervene (87%)
T/F: WEEV requires an additional bridge mosquitoe,
False. WEEV only requires Culex tarsalis. No additional mosquito is needed.
Lyme disease is vectored by ___________ ticks and its reservoir is usually ___________. It is NOT reservoired by _______, which only carry/transport the tick
Lyme disease is vectored by __Ixodes spp._ ticks and its reservoir is usually _sylvantic rodents__.
It is NOT reservoired by _deer_, which only carry/transport the tick
WNV is maintained in a mosquito-‐________-‐mosquito cycle
bird
___________
Primarily transmitted by Culex spp. mosquitoes
Birds maintain viremia for 1-‐4 days post exposure
What is the term to describe an Animal is bought by plant operator, subject to passing inspection. Seller is only paid for those parts passing inspection.
Subject to Inspection
T/F: contact with blood, urine, and feces are not considered exposures to rabies
true- only if through bite or non-bite routes (organ transplant, aerosol, butchering carcass, unpasteurized milk)
What is the distribution of Chikungunya? How is it transmitted?
mosquito vectored
Typically “lives” in Asia, Africa, and the Indian Subcontinent,
BUT it recently spread to St. Marten and then spread from there