EP Flashcards

1
Q

Class 1c Antiarrhythmic

A

Flecanide

Propafenone

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2
Q

Class 1c Mechanism

A
Slows conduction
Blocks open Na channels 
Dissociate slowly during diastole
Effective at high heart rates 
“Use dependence”
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3
Q

Class 1a antiarrhythmics

A

Quinidine

Procainamide

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4
Q

Class 1b antiarrhythmics

A

Mexilitine

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5
Q

Class III antiarrhythmics

A

Sotalol

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6
Q

Class III mechanism of action

A

Blocks potassium channels
Prolonged depolarization
Prolonged action potential
Prolonged refractory period

“Reverse use dependence”
More effective at slower heart rates
Daily medication for maintenance of sinus rhythm

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7
Q

Class 1b Mechanism if Action

A

Increase rate of depolarization
Increase delayed afterdepolarization

Shorten refractory period

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