Enzymes and the principles of catalysis

Question 1

What are the constatns in the Michaelis-Menten model?

Answer 1

Vmax: maximum rate of enzyme kinetics

Km: [substrate] at ½Vmax

• this is the affinity to which the enzyme binds its substrate
• lower Km = tighter substrate binding and faster rate of reaction.

Question 2

What is the equation for reaction velocity in the Michaelis-Menten model?

Answer 2

v = Vmax [S] /

Km + [S]