Enzymes and Coenzymes

Question 1

How do enzymes speed up reactions?

Answer 1

Lower activation energy
- By weakening bonds withing the substrate when the active site is in contact with substrate
- Makes bonds easier to break

Question 2

Competitive inhibitors effect on rate of enzyme reaction

Answer 2

Bind to active site, but can be displaced if substrate concentration is high enough (reversible)

Question 3

Non-competitive inhibitors effect on rate of enzyme reaction

Answer 3

Bind to allosteric site, changing shape of enzyme so no longer complementary (irreversible)

Question 4

Co-Factors

Answer 4

Bind to active site and increase affinity to substrate

i.e. ATP, NADH, NADPH, FADH2