Enzymes

Question 1

enzymes that follow Michaelis-Menten reaction have what curve

Answer 1

hyperbolic

Question 2

the higher the Km, the __ the affinity

Answer 2

lower

Question 3

NADH derived from

Answer 3

niacin B3

Question 4

FADH drived from

Answer 4

riboflavin B2

Question 5

only non protein component of ETC

Answer 5

ubiquinone coQ

Question 6

Complex I aka

Answer 6

NADH DH

NADH:CoQ oxidoreductase

Question 7

Complex II aka

Answer 7

Succinate DH

Question 8

Complex III aka

Answer 8

cyt b-c1 complex

coQ:c1 oxidoreductase

Question 9

Complex IV aka

Answer 9

cyt c oxidase

Question 10

Complex I inhibitors

Answer 10

barbiturates, piercidin A, amytal, rotenone

Question 11

Complex II inhibitors

Answer 11

malonate, carboxin, TTFA

Question 12

Complex III inh

Answer 12

antimycin A, dimercaprol

Question 13

Complex IV inh

Answer 13

cyanide, CO, sodium azide, HS

Question 14

encephalomyopathy clinically characterized by shor stature, stroke-like episodes, migrainous headaches, vomiting, seizures, and lactic acidosis

Answer 14

MELAS

mitoch enceph, LA, stroke-like episodes

Question 15

point mutations in mitochondrial DNA result to loss of retinal ganglion cell, leading to late onset acute optic neuropathy and bilateral central vision loss d/t mutation in NADH DH

Answer 15

Leber Heriditary Optic Neuropathy (LHON)