enzymes Flashcards

1
Q

What is an enzyme

A

Ccmplex globular protein

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2
Q

what shape is the enzyme

A

roughly spherical tertiary structure Which is very specific in shape.which is 3 dimensional

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3
Q

what do the metabolic reactions depend on

A

the-enzymes

Which act as a catalyst

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4
Q

What does a catalyst do

A

Speed up the reactions in the body. Theyalso control the speed at which the action takes place.

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5
Q

Why do enzymes have a specific shape called the active site

A

The active site is complementary to the sub strate , which fits into the active site making the reactions occur more quickly

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6
Q

Why are enzymes highly Sspecific

A

Because only one substrate fit into the enzymes active site

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7
Q

What do we call the input of energy which kickstaarts the reaction

A

Activation energy

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8
Q

What is needed to get past the energy barrier

A

Heat

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9
Q

Why are enzymes needed in the body

A

Because at 37c there is not enough kinetic energy to get past the energy barrier

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10
Q

What temperature are most of the body’s reactions taking place at

A

37c

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11
Q

What is the term for when a substrate fit into an active site of an emzyme

A

The lock and key theory

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12
Q

What are the main 3 points in the induced fit

A
  1. It has a base flexible shape
  2. The substrate collides with the enzymes so enzyme change schape
  3. The activation energy lowers
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13
Q

What are the 2 ways in which the enzyme can be effected

A

The temperature and the Ph

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14
Q

If the temperature increases what happens about the kinetic energy

A

The kinetic energy increases increasing the collisions wit hthe active sites becasue they move faster

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15
Q

Why is it band if the enzymes vibrate to much

A

Enzymes are made of hydrogen bonds which are relatively weak so if it vibrates more because of the texture then theynmsy break changing the shape of the active site

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16
Q

What is denatured enzyme

A

This is where the the substrate still fits in but not as easily so the rate of reaction slows down however more bonds break soothe substrate can no longer fit into the enzyme becasuebthey active site changes so Much

17
Q

What is the optimum texture for a human enzyme to work at the best

18
Q

Whatbdoes the Ph measure

A

The concentrations of H+ ions

19
Q

What happens to the enzyme if the hydrogen varies to much

A

It changes the charge on the molecules

And breaks down these bonds as they’re weak hydrogen bonds

20
Q

If the hydrogen varies to much hoe does the enzyme denaturtues

A

The tersionary structure changes so the active site is no longer the right shape

21
Q

If a fix amount of enzymes are present and the amount of substrate present slowly increases the rate of reaction this is because

A

A low substrate concentration means that some of the enzymes will have empty active sites. There is not enough substrate moleculesn present for the enzyme to work the fastest

22
Q

If the concentration of substrate increases to a certain point what will happen

A

There will be no difference in the reaction this is becasuebthey all the active sites are being used so molecules are waiting for an active site

23
Q

What does the blocked pancreatic duct mean with people with cystic fibrosis

A

The digestive enzyme produced in the pancreas can not enter the gut so food is not digested

24
Q

What was elastase do the cystic fibrosis sufferers

A

It damages elastic fibres causing damage in the lungs and airways

25
What does alpha 1 antitrypsin
It is an inhibitor of elastase and reduced the damage to the lungs and airways
26
What is emphysema
This is damage to the alveoils due to cigarettes cigarette smoke this reduces surfacenarea and makes it hard to breath in oxygen and get it to the body
27
What can emphysema be treated by
Alpha 1 antitrypsin
28
How can we diagnosis for enzymes
I'd glucosemisnin the urine you could have diabetics because you use the test strips in the urine when it changes colour the enzyme is reacting