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CnS > Enzymes > Flashcards

Enzymes Flashcards

1
Q

CYP3A4 inhibitors

A
  1. Amiodarone, verapamil, diltiazem, quinidine (VeDAQ)
  2. azithromycine, eryrhromycin, clarithromycin (ACE mycin)
  3. cyclosporine
  4. ethinyl estradiol
  5. azole antifungals
  6. protease inhibitors
  7. Grapefruit juices
  8. Ranitidine, cimetidine
  9. sertraline
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2
Q

CyP 3a4 inducers

A
  1. dexamethasone, rofecoxib
  2. glucocorticoids
  3. phenytoin, carbamazepine, phenobarbital
  4. progesterone
  5. rifampin, rifabutin, nelfinavir, sulfadimidine
  6. st.john’s wort
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3
Q

2D6 inducer

A

Dexamethasone

Rifampin

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4
Q

2D6 inhibitor

A
  1. AMIODARONE, DILTIAZEM, QUINIDINE
  2. CELECOXIB
  3. CITALOPRAM, CODEINE, PAROXETINE
  4. RANITIDINE
  5. YOHIMBINE
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5
Q

Bupropion enzyme inducer

A

2B6

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6
Q

Mirtazapine enzyme inducer (AAD)

A

1A2
3A4
2D6

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7
Q

Enzyme inducer of TrAzodone

A

3A4

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8
Q

Enzyme inducer of vortioxetine

A

2D6

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9
Q

Enzyme inducer of VilAzodone

A

3A4

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10
Q

Enzyme inducer of Amitryptyline

A

3A4

2C19

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11
Q

Enzyme inducer of Clomipramine

A

2D6

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12
Q

Enzyme inducer of Desipramine

A

2D6

2C19

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13
Q

Enzyme inducer of Doxepine

A

2D6

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14
Q

Enzyme inducer of ImiprAmine

A

2D6

3A4

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15
Q

Enzyme inducer of Nortryptyline

A

3A4

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16
Q

Enzyme inducer of Buspirone

A

3A4

17
Q

Monotherapy not recommended in Acute Mania

A

OmegaTopi of GaZoni in LamUrinol of Acute Mania

18
Q

Acute Mania not recommend combination of Carba and RisOla

A

Carbamazepine
Risperidone
Olanzapine

19
Q

Enzyme inducer of AlprAzolam

A

3A4

3A5

20
Q

Enzyme inducer of BromAzepam

A

2D6

1A2

21
Q

Enzyme inducer of clonazepAm

A

3A4

22
Q

Enzyme inducer of DIAzepam

A

3A4

2C19

23
Q

Enzyme inducer of MidAzolam

A

3A4

24
Q

Enzyme inducer of temAzepam

A

3A4

2C19

25
Q

Enzyme inducer of TriAzolam

A

3A4

26
Q

THUS BENZO HAS LIFE LESS THAN 5HRS

A

Zolams

27
Q

This BdZ have life between 5-24hrs

A

ZEPAMS +alprazolam

CnS (4 decks)

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