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CnS > Depression > Flashcards

Depression Flashcards

1
Q

Drug induce depression (5A, BC)

A 
Antipsychotic
Anti-parkinson
Anticonvulsant
Anticholinergic
Antiviral
Bb
CCB
Clonidine
Corticosteroids
Finasteride
Interpheron alpha/beta
Isotretinoin
Methyldopa
PPI and H2RA
Reserpine
Stimulant
Statins
Sex hormones
Triptans
Varenicline
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2
Q

Screening tools available for depression:

A
  1. Patient health questionnaire
  2. Mood disorder questionnaire
  3. HAM-D-7 (hamilton depression rating scale)
  4. EPDS (edinburg postnatal depression scale)
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3
Q

4 superior efficacy 1st line pharmacological treatment for depression: (SeVeM-Es)

A

Sertraline
Venlafaxine
Mirtazapine
Escitalopram

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4
Q

Primary metabolizing CYP enzyme for citalopram and escitalopram:

A

2C19 3A4

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5
Q

Primary metabolizing CYP enzyme for fluoxetine

A

2C9 2D6

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6
Q

Primary metabolizing CYP enzyme for fluvoxamine

A

1A2 2D6

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7
Q

Primary metabolizing CYP enzyme for Paroxetine IR and CR

A

2D6

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8
Q

Primary metabolizing CYP enzyme for sertraline

A

2D6

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9
Q

Primary lnhibitory CYP enzyme for fluoxetine

A

2C9
2C19
2D6
3A4

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10
Q

Primary inhibitory CYP enzyme for fluvoxamine

A

1A2
2C9
2C19
3A4

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11
Q

Primary inhibitory CYP enzyme for paroxetine

A

2D6

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12
Q

Primary inhibitory CYP enzyme for sertraline

A

2C19

2D6

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13
Q

Primary inhibitory CYP enzyme for duloxetine

A

2D6

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14
Q

Primary metabolizing CYP enzyme for venlAfaxine, desfenlAfaxine and levomilnAcipran

A

CYP 3A4

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15
Q

Primary metabplizing CYP enzyme for bupropion

A

CYP 2B6

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16
Q

Primary metabolizing CYP enzyme for mirtazapine

A

CYP 1A2
2D6
3A4

17
Q

1st metabolizing CYP enzyme for Amitryptyline

A

3A4

2C19

18
Q

1st metabolizing CYP enzyme for clomipramine

A

2D6

19
Q

1st metabolizing CYP enzyme for desipramine

A

2D6

2C19

20
Q

1st metabolizing CYP enzyme for Doxepin

A

2D6

21
Q

1st metabolizing CYP enzyme for Imipramine

A

2D6

3A4

22
Q

1st metabolizing CYP enzyme for Nortryptyline

A

3A4

23
Q

SsRI drugs

A 
Citalopram
Escitalopram
Fluoxetine
Fluvoxamine
Paroxetine
Sertraline

CnS (4 decks)

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