Enzyme Substrates- W. COAST Flashcards
1
Q
W
A
Warfarin
2
Q
C
A
Corticosteroids
3
Q
O
A
Oral Contraceptives
4
Q
A
A
Aminophylline/ Theophylline
5
Q
S
A
Statins
6
Q
T
A
Tricyclic Antidepressants
7
Q
What happens when an enzyme inducer interacts with these drugs?
A
Enzyme inducer will induce the metabolism/ clearance, so there will be lower concentrations of these drugs in the system, leading to ineffectiveness.
8
Q
What happens when an enzyme inhibitor interacts with these drugs?
A
Enzyme inhibitor will inhibit the metabolism/ clearance, so there will be higher levels of these drugs in the system, leading to toxicity.
