Enzyme Inducers and Inhibitors Flashcards
What mnemonic can be used to memorise enzyme inducers?
SCRAP GP.
Give some examples of enzyme inducers.
Sulphonylureas, carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital.
What mnemonic can be used to memorise enzyme inhibitors?
SICKFACES.COM.
Give some examples of enzyme inhibitors.
Sodium valproate, isoniazid, cimetidine, ketoconazole, fluconazole, alcohol, chloramphenicol, erythromycin, sulfonamides, ciprofloxacin, omeprazole, metronidazole.
Sulphonylureas - enzyme inducer or inhibitor?
Inducer.
Carbamazepine - enzyme inducer or inhibitor?
Inducer.
Rifampin - enzyme inducer or inhibitor?
Inducer.
Alcohol - enzyme inducer or inhibitor?
Both.
Phenytoin - enzyme inducer or inhibitor?
Inducer.
Griseofulvin - enzyme inducer or inhibitor?
Inducer.
Phenobarbital - enzyme inducer or inhibitor?
Inducer.
Sodium valproate - enzyme inducer or inhibitor?
Inhibitor.
Isoniazid - enzyme inducer or inhibitor?
Inhibitor.
Cimetidine - enzyme inducer or inhibitor?
Inhibitor.
Ketoconazole - enzyme inducer or inhibitor?
Inhibitor.