Enzyme Inducers and Inhibitors Flashcards

1
Q

What mnemonic can be used to memorise enzyme inducers?

A

SCRAP GP.

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2
Q

Give some examples of enzyme inducers.

A

Sulphonylureas, carbamazepine, rifampin, alcohol, phenytoin, griseofulvin, phenobarbital.

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3
Q

What mnemonic can be used to memorise enzyme inhibitors?

A

SICKFACES.COM.

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4
Q

Give some examples of enzyme inhibitors.

A

Sodium valproate, isoniazid, cimetidine, ketoconazole, fluconazole, alcohol, chloramphenicol, erythromycin, sulfonamides, ciprofloxacin, omeprazole, metronidazole.

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5
Q

Sulphonylureas - enzyme inducer or inhibitor?

A

Inducer.

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6
Q

Carbamazepine - enzyme inducer or inhibitor?

A

Inducer.

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7
Q

Rifampin - enzyme inducer or inhibitor?

A

Inducer.

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8
Q

Alcohol - enzyme inducer or inhibitor?

A

Both.

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9
Q

Phenytoin - enzyme inducer or inhibitor?

A

Inducer.

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10
Q

Griseofulvin - enzyme inducer or inhibitor?

A

Inducer.

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11
Q

Phenobarbital - enzyme inducer or inhibitor?

A

Inducer.

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12
Q

Sodium valproate - enzyme inducer or inhibitor?

A

Inhibitor.

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13
Q

Isoniazid - enzyme inducer or inhibitor?

A

Inhibitor.

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14
Q

Cimetidine - enzyme inducer or inhibitor?

A

Inhibitor.

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15
Q

Ketoconazole - enzyme inducer or inhibitor?

A

Inhibitor.

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16
Q

Fluconazole - enzyme inducer or inhibitor?

A

Inhibitor.

17
Q

Chloramphenicol - enzyme inducer or inhibitor?

A

Inhibitor.

18
Q

Erythromycin - enzyme inducer or inhibitor?

A

Inhibitor.

19
Q

Sulfonamides - enzyme inducer or inhibitor?

A

Inhibitor.

20
Q

Ciprofloxacin - enzyme inducer or inhibitor?

A

Inhibitor.

21
Q

Omeprazole - enzyme inducer or inhibitor?

A

Inhibitor.

22
Q

Metronidazole - enzyme inducer or inhibitor?

A

Inhibitor.

23
Q

Grapefruit - enzyme inducer or inhibitor?

A

Inhibitor.