Enzyme Cooperativity Flashcards
1
Q
What are the two types of cooperativity
A
Positive and negative
2
Q
Explain positive cooperativity
A
The binding of a substrate to one subunit increases the affinity of the other subunits for substrate
3
Q
What does the term tense vs relaxed refer to for enzyme cooperativity
A
Low substrate affinity = tense
Increased substrate affinity = relaxed
4
Q
Explain negative cooperativity
A
The binding of a substrate to one subunit reduces the affinity of the other subunits for substrate
5
Q
What is a sigmoidal curve
A
Results from positive cooperative binding
