entresto Flashcards

1
Q

What is Entresto primarily used to treat?

A

Heart failure.

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2
Q

True or False: Entresto is a combination of two medications.

A

True.

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3
Q

What are the two active components of Entresto?

A

Sacubitril and valsartan.

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4
Q

Fill in the blank: Entresto works by inhibiting __________.

A

neprilysin.

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5
Q

What class of drug is valsartan?

A

Angiotensin receptor blocker (ARB).

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6
Q

Multiple Choice: Which of the following is a common side effect of Entresto?
A) Cough
B) Dizziness
C) Both A and B
D) None of the above

A

C) Both A and B.

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7
Q

What is the recommended starting dose of Entresto for most patients?

A

49/51 mg twice daily.

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8
Q

True or False: Entresto can be used in patients with a history of angioedema.

A

False.

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9
Q

What is the main benefit of using Entresto over traditional ACE inhibitors?

A

Greater reduction in heart failure-related hospitalizations and cardiovascular death.

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10
Q

Fill in the blank: Entresto should not be used with __________.

A

ACE inhibitors.

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11
Q

What type of heart failure is Entresto indicated for?

A

HFrEF (heart failure with reduced ejection fraction).

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12
Q

Multiple Choice: What is a contraindication for using Entresto?
A) Hypotension
B) Pregnancy
C) Both A and B
D) None of the above

A

C) Both A and B.

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13
Q

True or False: Entresto can cause hyperkalemia.

A

True.

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14
Q

What should be monitored regularly in patients taking Entresto?

A

Kidney function and potassium levels.

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15
Q

Fill in the blank: The brand name for sacubitril/valsartan is __________.

A

Entresto.

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16
Q

What is the mechanism of action of sacubitril?

A

It inhibits neprilysin, leading to increased levels of natriuretic peptides.

17
Q

Multiple Choice: Which of the following populations might benefit most from Entresto?
A) Patients with HFrEF
B) Patients with HFpEF
C) Patients with no heart failure
D) All of the above

A

A) Patients with HFrEF.

18
Q

True or False: Entresto is taken once a day.

19
Q

What is a common initial titration strategy for Entresto?

A

Increase the dose after 2-4 weeks based on tolerance.