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Entrance test Flashcards

Drugs

1
Q

Benzylpenicillin Na, K

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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2
Q

Benzylpenicillin procaine

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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3
Q

Benzylpenicillin benzathine

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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4
Q

Phenoxymethyl penicillin

A

Beta lactam AB –> Penicillins –> Narrow spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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5
Q

Oxacillin

A

Beta lactam AB –> Penicillins–> Penicillinase stable penicillins
Mode of action –> time dependent bactericidal
Mechanism of action –> inhibition of cell wall synthesis

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6
Q

Cloxacillin

A

Beta lactam AB –> Penicillins –> Penicillinase stable penicillin
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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7
Q

Dicloxacillin

A

Beta lactam AB –> Penicillins –> Penicillinase stable penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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8
Q

Flucloxacillin

A

Beta lactam AB –> Penicillins –> Penicillinase stable penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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9
Q

Amoxicillin

A

Beta lactam AB –> Penicillins –> Broad spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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10
Q

Ampicillin

A

Beta lactam AB –> Penicillins –> Broad spectrum penicillins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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11
Q

Ticarcillin

A

Beta lactam AB –> Penicillins –> Penicillins acting against Pseudomonas species
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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12
Q

Piperacillin

A

Beta lactam AB –> Penicillins –> Penicillins acting against Pseudomonas species
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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13
Q

Clavulanic acid

A

Beta lactam AB –> Beta lactamase inhibitors
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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14
Q

Sulbactam

A

Beta lactam AB –> Beta lactamase inhibitors
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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15
Q

Tazobactam

A

Beta lactam AB –> Beta lactamase inhibitors
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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16
Q

Cephazoline

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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17
Q

Cephapirin

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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18
Q

Cefadroxil

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dendent bactercidal
Mechanism of action: Inhibition of cell wall synthesis

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19
Q

Cephalexin

A

Beta lactam AB –> 1st generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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20
Q

Cefuroxime

A

Beta lactam AB –> 2nd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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21
Q

Ceftiofur

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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22
Q

Cefovecin

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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23
Q

Ceftriaxone

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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24
Q

Cefotaxime

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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25
Q

Ceftazidime

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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26
Q

Cefoperazone

A

Beta lactam AB –> 3rd generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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27
Q

Cefquinome

A

Beta lactam AB –> 4th generation Cephalosporins
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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28
Q

Imipenem

A

Beta lactam AB –> Carbapenems
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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29
Q

Meropenem

A

Beta lactam AB –> Carbapenems
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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30
Q

Aztreonam

A

Beta lactam AB –> Monobactams
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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31
Q

Tigemonam

A

Beta lactam AB –> Monobactams
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

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32
Q

Streptomycin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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33
Q

Neomycin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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34
Q

Paromycin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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35
Q

Kanamycin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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36
Q

Gentamicin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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37
Q

Tobramycin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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38
Q

Amikacin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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39
Q

Apramycin

A

Aminoglycosides
Mode of action: Concentration dependent bactericidal
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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40
Q

Spectinomycin

A

Aminoglycosides
Mode of action: BACTERIOSTATIC (only AG)
Mechanism of action: inhibition of protein synthesis (30S subunit), mistranslation

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41
Q

Chlortetracycline

A

Tetracycline –> short acting
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (30S)

42
Q

Oxytetracycline

A

Tetracycline –> short acting
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (30S)

43
Q

Tetracycline

A

Tetracycline –> short acting
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (30S)

44
Q

Doxycycline

A

Tetracycline –> long acting
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (30S)

45
Q

Minocycline

A

Tetracycline –> long acting
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (30S)

46
Q

Erythromycin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

47
Q

Azithromycin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

48
Q

Clarithromycin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

49
Q

Spiramycin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

50
Q

Tylosin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

51
Q

Tylvalosin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

52
Q

Tilmicosin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

53
Q

Tulathromycin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

54
Q

Gamithromycin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

55
Q

Tildipirosin

A

Macrolides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

56
Q

Lincomycin

A

Lincosamides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

57
Q

Clindamycin

A

Lincosamides
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

58
Q

Tiamulin

A

Pleuromutilins
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

59
Q

Valnemulin

A

Pleuromutilins
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

60
Q

Chloramphenicol

A

Phenicols
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

61
Q

Florefenicol

A

Phenicols
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

62
Q

Thiamphenicol

A

Phenicols
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis (50S)

63
Q

Bacitracin

A

Peptide AB –> Polypeptide AB
Mode of action: Concentration dependent bactericidal
Mechanism of action: They act like cationic detergent

64
Q

Polymyxin B

A

Peptide AB –> Polypeptide AB
Mode of action: Concentration dependent bactericidal
Mechanism of action: They act like cationic detergent

65
Q

Polymyxin E = Colistin

A

Peptide AB –> Polypeptide AB
Mode of action: Concentration dependent bactericidal
Mechanism of action: They act like cationic detergent

66
Q

Vancomycin

A

Peptide AB –> Glycopeptide AB
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

67
Q

Teicoplanin

A

Peptide AB –> Glycopeptide AB
Mode of action: Time dependent bactericidal
Mechanism of action: Inhibition of cell wall synthesis

68
Q

Rifampicin

A

Rifamycines
Mode of action: Time dependent bactericidal
Mechanism of action: inhibit bacterial DNA dependent RNA polymerase

69
Q

Mupirocin

A

Pseudomonic acid
Mode of action: bactericidal
Mechanism of action: inhibition of cell wall synthesis

70
Q

Fosfomycin

A

Phosphonic acid derivate
Mode of action: bactericidal
Mechanism of action: inhibition of cell wall synthesis

71
Q

Fusidic acid

A

Fusidic acid
Mode of action: bacteriostatic
Mechanism of action: inhibition of protein synthesis

72
Q

Sulfadimidine

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

73
Q

Sulfadiazine

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

74
Q

Sulfachlorpyridazine

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

75
Q

Sulfachlorpyrazine

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

76
Q

Sulfamethoxazole

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

77
Q

Sulfadoxine

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

78
Q

Sulfaquinoxaline

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

79
Q

Sulfasalazine

A

Sulphonamides
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

80
Q

Trimethoprim

A

Diaminopyrimidines
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

81
Q

Baquiloprim

A

Diaminopyrimidines
Mode of action: separately bacteriostatic and combination: time dependent bactericidal
Mechanism of action: inhibition of folic acid synthesis

82
Q

Nalidixic acid

A

Fluoroquinolones –> 1st generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

83
Q

Flumequine

A

Fluoroquinolones –> 2nd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

84
Q

Norfloxacin

A

Fluoroquinolones –> 2nd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

85
Q

Ciprofloxacin

A

Fluoroquinolones –> 2nd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

86
Q

Enrofloxacin

A

Fluoroquinolones –> 2nd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

87
Q

Danofloxacin

A

Fluoroquinolones –> 2nd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

88
Q

Difloxacin

A

Fluoroquinolones –> 2nd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

89
Q

Marbofloxacin

A

Fluoroquinolones –> 2nd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

90
Q

Levofloxacin

A

Fluoroquinolones –> 3rd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

91
Q

Sparfloxacin

A

Fluoroquinolones –> 3rd generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

92
Q

Pradofloxacin

A

Fluoroquinolones –> 4th generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

93
Q

Moxifloxacin

A

Fluoroquinolones –> 4th generation
Mode of action: concentration dependent bactericidal
Mechanism of action: inhibition of DNA synthesis

94
Q

Nitrofurantoin

A

Nitrofurans
Mode of action: bactericidal
Mechanism of action: destroy the DNA of bacteria

95
Q

Furazolidone

A

Nitrofurans
Mode of action: bactericidal
Mechanism of action: destroy the DNA of bacteria

96
Q

Metronidazole

A

Nitroimidazoles
Mode of action: concentration dependent bactericidal
Mechanism of action: destroy the DNA of bacteria

97
Q

Ronidazole

A

Nitroimidazoles
Mode of action: concentration dependent bactericidal
Mechanism of action: destroy the DNA of bacteria

98
Q

Tinidazole

A

Nitroimidazoles
Mode of action: concentration dependent bactericidal
Mechanism of action: destroy the DNA of bacteria

99
Q

Bacteriostatic agents

A
  1. Tetracyclines
  2. Macrolides
  3. Phenicols
  4. Pleuromutilins
  5. Lincosamides
  6. Fusidic acid
  7. Sulfonamides (in combi: time dependent bactericidal)
  8. Diaminopyrimidines (in combi: time dependent bactericidal)
  9. Spectinomycin –> only Aminoglycoside (rest: conc.dep.cidal)
100
Q

Time dependent bactericidal

A
  1. Penicillins (narrow, broad spectrum, penicillinase stable, penic. acting against pseudomonas)
  2. Beta lactamase inhibitors
  3. Cephalosporins
  4. Carbapenems
  5. Monobactams
  6. Polypetide AB–> only Glycopeptide ABs
  7. Rifamycines
  8. IF COMBI: Sulphonamides
  9. IF COMBI: Diaminopyrimidines

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