Enterobacteriaceae

Question 1

Enterobacteriaceae

• Structure
• Agar
• Lab investigations
• Hospital acquired?

Answer 1

GNR

• MacConkey Agar for lactose F differentiation of GNR
• turn red if ferments lactose
• Mass spectrometry
• • by detecting Somatic O, Flagella H

GNR is top cause of HAP - including P.Aeruginosa, HiB and Intestinal

• second then is Staph Aureus
• Bronchopneumonia

Question 2

E. Coli

• 3 damages
• location

Answer 2

TOP CAUSE OF UTI UTI UTI, BILIARY BILIARY BILIARY

TOP CAUSE OF SEPSIS/Bacteremia

• neonatal sepsis, meningitis
• • esp w congenital deformity allowing entrance into spinal cord
• Major cause of Diarrhoea too

Found normally in gut, just not virulent

Question 3

Why wahmen can get E. Coli UTI

Why guys can get E. Coli UTI

Answer 3

Wahmen - short urethra

Newborn boys - w urethral valves

Question 4

Note as long as there’s any obstruction
- lead to UTI or biliary tract infections

• fluke helminths, tumor whatever

Note contaminated food and fecal oral for E. Coli outbreaks

Answer 4

okie

Question 5

Severe E. Coli stuff [4]

Answer 5

Enterohemorrhagic E. Coli EHEC

Shigatoxigenic EC STEC - Hemolytic Uremic Syndrome

• • O157 H7
• • Hemolytic uremic syndrome (HUS) is a condition that can occur when the small blood vessels in your kidneys become damaged and inflamed. This damage can cause clots to form in the vessels. - Kidney failure;

Verotoxigenic EC VTEC - HUS

Other is Enterotoxigenic EC ETEC

Question 6

Salmonella groupies and species

Answer 6

Typhoid Fever causing | Enterogastritis causing

Typhoid Fever aka Enteric Fever

• systemic invasive!!!
• S. Typhi, S. Paratyphi

Gastroenteritis - can have invasion and fever too
- S. Enteritidis and others lmao

Question 7

What is typhoid fever vs gastroenteritis and how does it present

Answer 7

GE: diarrhoe

TF: constipation more common; rose spots

Question 8

How does salmonella spread

Answer 8

Fecal Oral, food contamination

• Salmonella causing GE more of POULTRY

Question 9

Typhoid fever diagnosis and prevention

Answer 9

Blood culture
- stool need check blood culture also

Sanitation, clean water TOP; vaccine for at risk

Question 10

Parasitic and Bacteria causes of dysentery

Answer 10

Amoeba

Shigella !!!

Question 11

Gimme the bacterias for HAP

Answer 11

Top is GNR -Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae,
- Staph Aureus

KNOW KLEBSIELLA is a EBAE

• HiB is more CAP

Question 12

Klebsiella

• structure
• location
• damages

Answer 12

• CAPSULATED GNR
• found in the normal flora of the mouth, skin, and intestines,
• • cause problems when aspirated; not spread by air

UTI, Lung Abscess, Nocosomial pneumoniae!!! HAP HAP HAP