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GI Micro (Quick) > Enterics/Anaerobes I > Flashcards

Enterics/Anaerobes I Flashcards

1
Q

Antiphagocytic capsule

A

B. fragilis

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1
Q

GI anaerobic abscesses

A

B. fragilis

Clostridium

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2
Q

Only G+ spore formers

A

Clostridium

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2
Q

Vaccine = formalin inactivated toxin

A

Clostridium tetani

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3
Q

A1 fragment ADP-ribosylates GTP binding protein (which incr CFTR, causing osmotic diarrhea)

A

V cholera

V Parahaemolyticus

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3
Q

Black tar heroine users

A

Clostridium botulinum

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4
Q

Rho-family GTPase rearranges actin + stress fibers

A

Clostridium diff

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5
Q

Associated w/ poor sanitation

A

V cholera

V Parahaemolyticus

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5
Q

Only anaerobic endospore formers

A

Clostridium

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6
Q

Disease due to exotoxins and hydrolytic enzymes

A

Clostridium

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7
Q

Abrupt + severe diarrhea + dehydration

A

V cholera

V Parahaemolyticus

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8
Q

Acute mesenteric lynphadenitis

A

Yersinia enterocolitica

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9
Q

Fe-sequestering

A

V vulnificus

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9
Q

Descending flaccid paralysis

A

Clostridium botulinum

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10
Q

Swarming on motility test

A

Proteus

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10
Q

Curved, G-, oxidase +

A

V cholera V Parahaemolyticus

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11
Q

Aggressive abx: clinda, erythromycin, metronidazole

A

B. fragilis

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12
Q

Toxin B = kills colon cells

A

Clostridium diff

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13
Q

“boxcar” bacili

A

Clostridium perfringens

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14
Q

severe watery diarrhea

A

V. cholera

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14
Q

KIA Slant = yellow w/ gas

A

lactose fermented (E. coli, Klebsiella, Enterobacter)

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14
Q

G+ tennis rackets/lollipops

A

Clostridium tetani

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14
Q

Exotoxin mediated = abx don’t work

A

Clostridium tetani

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16
Q

lockjaw + risus sardonicus 1-2wks post exposure

A

Clostridium tetani

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18
Q

Dysentery

A

Shigella

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19
Q

Non-invasive toxin

A

V cholera V Parahaemolyticus

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20
Q

Tryptophan –> Indole

A

Shigella (negative = Salmonella)

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20
Q

Wound inf in fishermen

A

V vulnificus

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21
Q

KIA Slant = Black w/ gas

A

glu fermented, H2S formed (Salmonella, Proteus)

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21
Q

Motile w/ polar flagella

A

V cholera

V Parahaemolyticus

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22
Q

Raw meat/milk with human-human transmission

A

Campylobacter jejuni Campylobacter fetus

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22
Q

Non-inflmm watery diarrhea for 8-12h (no fever, no vomiting)

A

Clostridium perfringens

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23
Q

“Sea gull” appearance

A

Campylobacter jejuni Campylobacter fetus

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24
Q

Incr risk if vit K deficiency (liver disease)

A

V vulnificus

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25
Q

Black colonies

A

P melaninogenic

26
Q

Rice water stool

28
Q

Negative motility test

A

Shigella, Klebsiella

28
Q

Dx via TCBS + MacConkey Agar

A

V cholera V Parahaemolyticus

30
Q

AB exotoxin, phage encoded

A

V cholera V Parahaemolyticus

31
Q

Infant diarrhea

31
Q

Slender, curved G- rod

33
Q

Small dose = massive death

A

Campylobacter jejuni Campylobacter fetus

34
Q

Non-invasive bacteria = not eliminated by host

36
Q

Purple on EMB

A

weak lactose fermenters (Klebsiella)

36
Q

Toxin A = diarrhea

A

Clostridium diff

38
Q

Grows in higher pH

A

V cholera

V Parahaemolyticus

38
Q

Vomiting, diarrhea, abd cramps

A

V vulnificus

39
Q

KIA Slant = completely red

A

no carb fermentation (Pseudomonas)

41
Q

Pseudomembraneous colitis

A

Clostridium diff

42
Q

Trx = metronidazole

A

Clostridium diff

43
Q

AB neurotoxin = tetanospasmin

A

Clostridium tetani

45
Q

Cleavage of V-snares and T-snares

A

Clostridium botulinum

46
Q

Toxin-coregulated pilus needed for GI colonization

A

V cholera V Parahaemolyticus

47
Q

Cultured microaerobically

A

Campylobacter

48
Q

grow at 42’C

A

Campylobacter jejuni

Campylobacter fetus

49
Q

CN damage (vision, dysphagia) –> resp failure

A

Clostridium botulinum

51
Q

G-, oxidase +, spirals

A

Campylobacter jejuni

Campylobacter fetus

52
Q

VacA + CagA on PAI

53
Q

Fluoroquinolone resistance

A

Campylobacter jejuni Campylobacter fetus

55
Q

raw canned foods, honey

A

Clostridium botulinum

57
Q

Causes Guillan-Barre Syndrome (oligo saccharide abs w/ myelin protein)

A

Campylobacter jejuni

Campylobacter fetus

58
Q

clips V-snare via Zn metalloprotease

A

Clostridium tetani

58
Q

7 antigenic types (A-G)

A

Clostridium botulinum

59
Q

Diarrhea form seafood

A

V. parahaemolyticus

61
Q

Fever, then bloody diarrhea w/ pus

A

Campylobacter jejuni Campylobacter fetus

63
Q

Related to clinda, imipenem, ceftaxidine, moxifloxacin

A

Clostridium diff

64
Q

Pink/red on MacConkey Agar

A

E. coli (lac+)

64
Q

Hyperbaric oxygen, PCN, protein-inh for enzymes

A

Clostridium perfringens

66
Q

alpha-PLC, collagenases, proteases

A

Clostridium perfringens

67
Q

Infects lining of small intestine, causes systemic spread

A

Campylobacter jejuni

Campylobacter fetus

69
Q

Green + metallic sheen on EMB

A

lactose fermenters (E. coli)

70
Q

Clear/white on MacConkey Agar

A

Shigella/Salmonella (lac-)

72
Q

Semi-selective + differential media

A

EMB MacConkey Agar

73
Q

US Gulf Coast

A

V vulnificus

74
Q

Blistering, hemorrhagic bullae

A

V vulnificus

75
Q

KIA Slant = red w/ yellow butt

A

glu fermented only (Shigella)

76
Q

Floppy Baby Syndrome

A

Clostridium botulinum (toxin B)

77
Q

Clear on EMB

A

nonlactose fermenters (Salmonella)

78
Q

Food poisoning (diarrhea, cramps, vomiting)

A

Salmonella typhimurium

80
Q

Aquatic ecosystems

A

V cholera

V Parahaemolyticus

81
Q

Sorbitol negative

82
Q

Gas gangrene + myonecrosis

A

Clostridium perfringens

83
Q

Fever + Watery –> bloody diarrhea

A

Clostridium diff

84
Q

Common in DM

A

Clostridium perfringens

85
Q

Serotypes include O1 (LPS) and O139

A

V cholera

V Parahaemolyticus

86
Q

toxin blocks release of GABA and glycine

A

Clostridium tetani

87
Q

MC in warm months

A

V cholera V Parahaemolyticus

GI Micro (Quick) (3 decks)

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