Enfermedad Trofoblástica Gestacional Flashcards
¿Qué es la enfermedad trofoblástica gestacional?
Es un grupo raro de tumores que involucran un crecimiento anormal de las células del trofoblasto, que normalmente formarían la placenta durante el embarazo.
Histológicamente existe una proliferación, tumefacción y ausencia de vasos sanguíneos en las vellosidades.
True or False: Molar pregnancy is a type of gestational trophoblastic disease.
True
What are the two main types of molar pregnancies?
Complete molar pregnancy and partial molar pregnancy.
Fill in the blank: The most common symptom of gestational trophoblastic disease is __________.
abnormal vaginal bleeding.
What hormone is typically elevated in patients with gestational trophoblastic disease?
Human chorionic gonadotropin (hCG).
What is the primary method of diagnosing gestational trophoblastic disease?
Ultrasound examination.
True or False: Gestational trophoblastic disease can lead to cancer.
True
What is the risk factor most commonly associated with gestational trophoblastic disease?
Maternal age, particularly women over 35 or under 20.
What is the treatment of choice for a complete molar pregnancy?
Suction curettage.
Fill in the blank: Patients with gestational trophoblastic disease require follow-up hCG monitoring for __________ months.
6 to 12.
What is choriocarcinoma?
A type of gestational trophoblastic neoplasm that can develop from a molar pregnancy.
True or False: Gestational trophoblastic disease can occur after a normal pregnancy.
True
What is the typical age range for women affected by gestational trophoblastic disease?
Women aged 20 to 40 years.
What imaging technique is used to assess the extent of gestational trophoblastic disease?
Pelvic ultrasound.
What is the role of chemotherapy in treating gestational trophoblastic neoplasia?
It is used to treat persistent disease or malignant forms.
Fill in the blank: The presence of __________ in the uterus can indicate a molar pregnancy.
grape-like cysts.
What follow-up procedure is recommended after treatment for gestational trophoblastic disease?
Regular monitoring of hCG levels.
True or False: A partial molar pregnancy has a normal fetus.
False
What is the incidence rate of gestational trophoblastic disease?
Approximately 1 in 1,000 pregnancies.
What are potential complications of untreated gestational trophoblastic disease?
Severe bleeding, metastasis, and infertility.
What is the most common demographic factor influencing the risk of gestational trophoblastic disease?
Ethnicity, with higher rates in Asian populations.
What is the significance of the ‘snowstorm’ appearance in ultrasound?
It is indicative of a complete molar pregnancy.
Fill in the blank: The primary cell type involved in gestational trophoblastic disease is __________.
trophoblasts.
What is the first-line treatment for choriocarcinoma?
Chemotherapy.
