Endterm Flashcards
A type of external beam radiation therapy (EBRT), stereo means 3-dimentional and tactic means probe, allows radiation beam to be given to a very specific are usually the brain, best for very small tumors, it can be completed in one-five days rather than over several weeks
Stereotatic radiotherapy
Delivers a single high dose of radiation to the tumor (called single fraction), this treatment doesn’t envolve surgery. An incision (cut) is not made and tissue is not surgically remove. __ is delivered by a team involving radiation oncologist and neurosurgeon.
Used to treat conditions involving the brain or spine including: CA that starts in the brain (gliomas, and other primary brain tumor, brain metastases, benign tumors arising from membranes covering the brain (meningiomas), abnormal blood vessels in the brain (arteriovenous malformations)
Stereotatic radiosurgery (SRS)
Gives smaller dose of radiation over a number of treatment sessions (called multiple fraction), until the desired total dose given, it also refers to one or several stereotatic radiation treatment in the body excluding brain or spine.
Small lung CA, lung metastases, liver metastases
Stereotatic radiotherapy (SRT)
When __ is used the head frame is attached to the skull. A neurosurgeon injects a local anesthesia just under the scalp to numb the area. Then the neurosurgeon places special screws or pins into the skull. These screws or pins fix the head frame to the skull. The skull screws and head frame are removed after the treatment is finished
Stereotatic radiosurgery (SRS)
When __ is used, a removable head frame or a special mask keeps the head in position
Stereotatic radiotherapy (SRT)
3 delivery systems
Gamma knife, linear accelerator, cyberknife
A type of conformal radiotheraphy. Conformal radiotherapy shapes the radiation beams to closely fit the area of the CA. It is an advanced mode of high-precision radiotherapy. Uses a computer controlled LINAC to deliver precise radiation dose to malignant tumor. Allows radiation dose to coform more precisely to 3-dimensional shape of tumor. Allows higher radiation doses to be focused on the regions within the tumor while minimizing the dose to surrounding normal critical structures
Intensity modulated radiotherapy (IMRT)
Currently, __ is being used most extensively to treat CA of the prostate, head and neck and CNS. Since __ uses a standard radiotherapy machine such as LINAC, it is excellent to use multi-leaf collimator
Intensity modulated radiotherapy (IMRT)
Persons involved in the procedure in IMRT
Radiation oncologist, medical physicist, dosimetrist, radiation therapist, radiation therapy nurse
What the px feels during and after the procedure
No pain during the actual treatment with IMRT
machine can be stopped if you experience discomfort due to treatment position or positioning devices
As treatment progress some px may experience treatment-related side effects
IMRT treatment sessions usually takes between?
10-30 mins
Early side effects
Depending on the area being treated, other early side effects may include
Hair loss in the treatment area
Mouth problems and difficulty in swallowing
Eating and digestion problems
Diarrhea
Nausea and vomiting
Soreness and swelling in the treatment area
Urinary and bladder changes
Late side effects
Which are rare, occurs months or years following treatment and are often permanent. They include
Infertility
Brain changes
Spinal cord changes
Lymphedema
Brachytherapy comes in to 2 treatment procedures:
High dose rate (HDR) brachytherapy and low dose rate (LDR) brachytherapy
A type of internal radiation therapy, delivers high dose of radiation from implants placed closed to or inside the tumor.
High dose rate brachytherapy
3 types of HDR brachytherapy
Intracavitary implant
Intraluminal implant
Interstitial implant
An applicator is inserted into a body cavity to reach the tumor. These are performed in clinic or out patient basis. Local anesthesia and/or conscious sedation is required
Intracavitary implant
The catheters are inserted into a tube structure such as bronchus, esophagus, or bile duct. These are treated the same as intracavitary implants
Intraluminal implants
Implants are done in operating room with the px under local, general or spinal anesthesia, interstitial catheters are inserted through the body tissue to encompass tumor. In case of prostate and gynecological cases, a rubber template is sutured to the outside skin to hold the treatment catheters in position, in breast and head and neck cases, the treatment catheters are held in position on the skin by plastic buttons where the catheters enter and exit the skin, it is by means of needles or catheters
Interstitial implant
Type of internal radiation therapy that delivers low doses of radiation from implants placed closed to or inside the tumor in the body, implants are the same as in the HDR. Sources used are: Ra-226, Cs-137, Ir-192, I-125 and Pa-103. Source handling and loading into the applicator or tissue can be performed manually or remotely by the afterloader with source loading performed by a computerized unit
Low dose rate brachytherapy (LDR)
In __, tiny radioactive particles the size of rice are implanted directly into the size of the tumor these particles are known as seeds
LDR brachytherapy
Measurement of the absorbed dose delivered by ionizing radiation calculation and assessment of radiation dose received by the human body used extensively for radiation protection and is routinely applied to occupational radiation workers
Dosimetry
dose absorbed unit in time. indicates the amount of radioactive dose received by the person within a certain period of time. Expressed in rems or sievert (Sv) per hour.
Dose rate
Ordinarily measured on the central axis at a standard source surface distance (SSD) at the depth of Dmax in phantom
Dose rate in tissue
Displays relative doses across the treatment plan consisting of multiple beams
Dose profile
4 radiation quantities and qualities
Quantity, (old), name (new), other units
Activity (A), curie(Ci), becquerel (Bq), Ci= 3.7x10^1, Bq 1Bq= dis/s
Absorbed dose (D), rad, gray(Gy) Gy= 100 rad j/kg, ms2/s2, 1 Gy= 1j/kg
Equivalent dose (H), rem, sievert (Sv) Sv=100 rem
Exposure (E), roentgen, coulomb/kg, R=2.58x10-4 c/kg
Used for all kinds of radiation for any material. Energy transferred by ionizing radiation to the interacting medium per unit mass. Unit dose that refers to dose received by the patients
Absorbed dose (D)
D=
E=
M=
Absorbed dose
Energy
Mass
Amount of radiation exposure received by the radiation workers, Unit used that refers to the dose received by the radiation workers
Formula H=DQN
Equivalent dose (H)
H=
D=
Q=
N=
Equivalent dose
Absorbed dose
Quality factor
20 for alpha radiation
10 for both proton and neutron
1 for both x-ray and gamma ray
Modifiying factor always equal to 1 (no unit)
Device that measure dose distribution within such phantoms The constancy of the machine must have been routinely checked otherwise irreversible harm may be caused either by overdosing – which lead to tissue damage or underdosing – which result in failure to cure. It is advisable to measure the dose actually delivered to the patient by means of __ placed in body cavities or in catheters or needles inserted in the tissues.
dosimeters
at a point is an absorber such as tissue in the energy deposited in small fixed weight of material
Dose or absorbed dose
When radiation beam reaches the patient, the dose delivered to a point within the patient depends on the following.
Dose measurements