Endothelium Flashcards
what are the 3 layers of arteries
- outer connective cells: tunica adventitia
- middle muscular smooth cells: tunica media
- inner endothelium: tunica intima
what is EDRF
endothelial derived relaxing factor (NO)
what are EDRFs
vasodilators
function of endothelins?
vasoconstrictor
function of prostacyclin in endothelium
inhibitors of platelet aggregation and vasodilator
function of adenosine in endothelium
vasodilator
function of antithrombin III
anti-clotting agent
function of plasminogen activator (TCA)
anti-clotting agent via stimulation of fibrinolysis
pinocytosis
the delivery of substances via vesicles
how is inactive NOS be activated
when CaCM binds with it
what and what is reacted together to make NO
NOS and L-arginine
what kind of drugs can help with high blood pressure due to RAAS
renin inhibitors
ACE inhibitors
AT1 antagonists1
what can stimulate the production of endothelins
adrenaline
angiotensinII
insulin
cortisol
thrombin
glucose
hypoxia
what are ETA receptors responsible for
vasoconstriction
