Endometrium

Question 1

Endometrial hyperplasia

Answer 1

dysfunctional uterine bleeding

• Elevated estrogen without opposition by progesterone stimulates growth of the uterine lining.
• Obesity is a risk factor for endometrial hyperplasia due to excess aromatization of androgens to estrogen in the adipose tissue.
• associated with prolonged exposure to estrogen without opposing progesterone, which may develop from chronic anovulation over many years.
• condition is most common in obese older women or those who receive estrogen without progesterone during hormone replacement therapy.