Endometriosis adenomyosis

Question 1

what is retrograde menstruation

Answer 1

blood flows back to different parts of reproductive system like ovary,fallopian tube,uterus,pouch of douglas
seen in 70-80 % of women worldwide

Question 2

cause of endometriosis

Answer 2

poor immunity due to which macrophages cannot clear blood and high estrogen
seen in 5-10% women

Question 3

how does smoking effects endometriosis

Answer 3

smoking decreases the chances of endometriosis as
smoking decrease aromatase enzyme
aromatase enzyme helps in conversion of androgen to estrogen

Question 4

age group of endometriosis risk factors

Answer 4

3rd-4th decade (25-35 YEARS)

Question 5

most common site of endometriosis

Answer 5

ovary , 2nd most common-pouch of douglas

Question 6

best technique for diagnosis of endometriosis

Answer 6

trans vaginal sonography(ground glass appearance of cyst is seen)

Question 7

why does infertility happens in endometriosis

Answer 7

• altered tubo-ovarian relation
• poor oocyte quality and reduction of ovulation
• poor embryo quality

Question 8

drug treatment for endometriosis

Answer 8

• depo medroxyprogesterone acetate-150mg/once every 3 months
• danazol-200-400 mg, 3 TAD
• COCP
• GnRH analogues

Question 9

first sign to stop danazol

Answer 9

hoarseness of voice

Question 10

what is the goal of medical management in endometriosis

Answer 10

stopping of periods

Question 11

what is the biggest side effect of GnRH analogues

Answer 11

osteoporosis (happens due to continuous gnrh for more than 6 months, it starts after 6 months aproxx)

Question 12

what is adenomyosis/endometriosis interna

Answer 12

endometriosis within the uterus / moves towards the myometrium

Question 13

size criteria of adenomyosis

Answer 13

<14 week size,uniformly enlarged uterus