Endogenous Retrovirus K promoter: a landing strip for inflammatory transcription factors? Flashcards
1
Q
Who authored this paper and when?
A
Sheena and Renée in 2013
2
Q
Reactivation of Endogenous Retroviruses are most commonly associated with what type of diseases?
A
Inflammatory
3
Q
Which ERV is the most recently endgenized and most transcriptionally active ERV in humans?
A
ERVK
4
Q
The abstract of this paper attributes ERV expression to be regulated by what?
A
epigenetic mechanisms and transcriptional regulatory elements present in the LTRs.
5
Q
ERV LTRs are responsive to what?
A
Viral and cellular transcription factors
6
Q
What is the basic function of this paper?
A
To explore inflammatory transcription factor sites in the ERVK LTRs and discuss possible ways ERVK is induced in inflammatory diseases.
