Endodrine dugs Flashcards
what drugs are sulfoylureas
glyburide, glipizide,
how do sulfonlyureas work
the stimulate pancreas to release more insulin
what drugs are biguanides
metformin
how do biguanides work
surpress hepatic gluconeogenesis
what drugs are thiazolidenediones (TZD)
piglitazone, rosiglitazone
how do thiazolidenediones work
decrease insulin resistance and increase sensitivity to insulin
what drugs are alpha glucosidase inhibitors
acarbose, miglitol
how do alpha glucosidase work
reduce glucose by delaying glucose absorption
how does Exantide work
lowers blood glucose by slowing gastric emptying stimulating pancreatic insulin response to glucose
how do cholesterol absorption inhibitor wokr
decrease intestinal absorption of dietary and biliary cholesterol
what drugs are cholesterol absorption inhibitors
Ezetimibe
what drugs are fibrate
gemfibrozil, fenofibrate
how do fibrates work
activate PPAR which modulates metabolism and catabolism of lipids
they increase the breakdown of VLDL
what drugs are nicotinic acid
Nicotinic acid, niacinamide, niacin
how do nicotinic acids work
decrease triglyceride synthesis
