Endocrinology - Kaplan

Question 1

Biphosphonates (Pamidronate, alendronate, ibandronate, risendronate):

Answer 1

1. Esophagitis - Should be taken sitting up while drinking a LOT OF WATER.
2. Hypocalcemia.
3. Osteomalacia.
4. Osteonecrosis of the jaw.

Question 2

PTU/Methimazole:

Answer 2

1. Neutropenia.
2. Lower granulocyte levels - Inhibiting bone marrow.
3. Purpuric skin lesions may also occur.