Endocrinology Flashcards

1
Q

What is endocrinology?

A

A collection of glands that produce hormones that regulate metabolism, growth and development, tissue function, sexual function, reproduction, sleep, and mood, among other things.

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2
Q

Where is the thalamus located?

A

Anterior neck C5-T1

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3
Q

What muscles does the thalamus lie behind?

A

sternohyoid and sternothyroid

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4
Q

What do the thalamus lie inferiorly to?

A

the thyroid cartilage of the larynx

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5
Q

Which arteries supply the thyroid?

A

superior and inferior thyroid arteries

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6
Q

Where does the superior thyroid artery arise from?

A

the first branch of the external carotid artery

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7
Q

Which portions of the gland does the superior thyroid artery supply?

A

the superior and anterior portions

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8
Q

Where does the inferior artery arise from?

A

thyrocervical trunk, a branch of the subclavian artery

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9
Q

What portion of the thalamus does the inferior artery supply?

A

postern-inferior aspect

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10
Q

What innervates the thalamus?

A

branches from the sympathetic trunk

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11
Q

What controls hormone release from the thalamus?

A

the pituitary gland

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12
Q

At 3-4 weeks what do the thyroid glands appear as?

A

an epithelial proliferation at the base of the pharynx

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13
Q

What happens to the epithelial proliferation at the base of the pharynx?

A

It migrates down the thyroglossal duct to below the larynx

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14
Q

At what week do the glands produce thyroxine?

A

18-20 weeks

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15
Q

Which 3 structures are seen in thyroid histology?

A
  • follicles
  • follicular cells
  • parafollicular/C cells
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16
Q

What do follicles contain?

A

thyroglobulin in which iodine is stored and taken up from the blood

17
Q

What is the epithelium of follicular cells?

A

Simple cuboidal BUT becomes columnar with increased metabolic activity

18
Q

How are follicular cells arranged?

A

In hollow circles called follicles

19
Q

What hormones do the follicles produce?

A

T3 and T4

20
Q

What do parafollicular/C cells produce?

A

calcitonin for Ca2+ homeostasis

21
Q

What is the endocrine system made up of?

A

The endocrine system is made up of the pituitary gland, thyroid gland, parathyroid glands, adrenal glands, pancreas, ovaries (in females) and testicles (in males)

22
Q

What does endocrinology mean in Greek?

A

“endo,” meaning within, and “crinis,” meaning to secrete

23
Q

How does endocrinology work?

A

a gland selects and removes materials from the blood, processes them and secretes the finished chemical product for use somewhere in the body.

24
Q

What two hormones does the thyroid gland produce?

A
Thyroxine T4 (contains 4 iodines)
Triiodothyronine T3 (contains 3 iodines)
25
Q

Which is the major thyroid hormone?

A

T3 because T4 is converted to T3 by enzymes known as doiodinases in target cells

26
Q

The concentration of which thyroid hormone is higher in the blood?

A

T4 (T4 = reservoir for T3)

27
Q

What is thyroxin made from?

A

tyrosine and iodine