Endocrinology

Question 1

low TSH, elevated T3/T4, no palpable abnormality but generally mildly enlarged gland, negative thyrotropin receptor Ab, positive thyroid peroxidase Ab

Answer 1

post-partum thyroiditis

Question 2

which Ab is elevated in Grave’s dx

Answer 2

thyrotropin receptor Ab

Question 3

next step in evaluation of patient with resistant HTN on 3+ medications including a diuretic? eval for hyperaldosteronism

Answer 3

renin/aldosterone ratio; serum renin activity is typically low and serum aldosterone is high

Question 4

the following are common side effects of which diabetes class of medications?
-headache
-nasopharyngitis
-URI/UTI
-elevated LFTs

these are associated with which other type of diabetes medication?
-hypovolemia
-UTI
candidiasis
-dehydration
-DKA

and this one?
-weight gain
-salt retention
-edema
-cardiovascular complications
-increased risk of fractures with long term use

Answer 4

1. DPP-4 inhibitors (ex. saxagliptin)
2. SGLT-2 inhibitors
3. thiazolidinediones

Question 5

patients chronically on metformin should have annual screening of which vitamin level? which can be decreased with this medication

Answer 5

metformin

Question 6

which class of DMII medications is associated with increased risk of necrotizing fasciitis of the perineum and other genitourinary infections?

Answer 6

SGLT2 inhibitors

Question 7

duration of action of various insulins:
a. tresiba
b. glargine
c. NPH
d. regular
e. short acting lispro

Answer 7

a. 42h
b. 11-24h
c. 12-16h
d. regular 5-8h
e. SA lispro 3-6.5h