Endocrinology Flashcards
What are Endocrine glands?
They secrete hormones (chemical messengers) to the blood or lymph and have no ducts
Function of the hypothalamus ?
Sexual behavior and production and release of hormones
What are hormones that activate the reproductive system?
- Gonadotropin Releasing Hormone (GnRH) –> LH FSH release
- Thyrotropin Releasing Hormone (TRH) –> TSH Prolactin release
Anterior Pituitary hormones?
Gonadotropins:
- FSH
- LH
- Prolactin
Posterior Pituitart hormones?
- Oxytocin (contracts smooth muscles)
- Anti Diuretic Hormone _ADH
What are 2 Gonadal polypeptide hormones?
- Relaxin: produced during pregnancy
- Inhibin: diminishes FSH release
Where are Gonadal steriod hormones found in the body?
Ovary, testis, adrenal gland
Types of steriod production?
-Androgens (testosterone)
- Estrogens (estadiol)
- Progestines (progesterone)
Estrus cycle
When female is sexually receptive (in heat) and ovulation
- includes follicular phase and luteal phase
What is the main hormone during estrus cycle in the Follicular phase?
Estrogen
What is the main hormone during estrus cycle in the Luteal phase?
structure- Corpus luteum
- Progesterone
What are the 3 phases of Menstrual cycle?
- 4-6 days of mestruation (peeking of endometrium)
- Follicular: 8-10 days - follicules produce estradiol - endometrium thickens
- Luteal: 14 days - CL produces progesterone and estrogen - continued thickening of the endometrium
What is Polyestrus?
having more than one period of estrus per year
(Cows, queen (cats), sow (pig))
what is seasonally polyestrus?
Those animals with estrous cycles occurring only during certain seasons of the year, due to the amount of daylight
such as horses (Long day breeders- spring) and ewe (sheep- short day breeders - autumn)
What is monoestrus?
having one estrous cycle per year.
such a dogs, wolves, and bears
What are the two phases in the Follicular phase during estrus cycle?
- Proestrus - formation of an ovulatin follicule & increased estradiol secretion
- Estrus - peak estradiol secretion induces receptive behavior and ovulation
What are the two phases in Luteal phase during estrus cycle?
- Metestrus - formation of corpus lutem from folicular cells & beginning of progesterone secertion
- Diestrus - prolonged luteal secretion of high progesterone levels
What happens during proestrus?
- preovulatory follicle grows
- Estradiol levesl rise
- Endometrial glands grow
- Peak estrogen
What happens during estrus?
- enables the male to breed
- estrogen levels decrease
- Ovulation 24- 48 hrs after peak LH
- increases mucus in cervix
What happens during Metaestrus?
- low estrogen levels
- ovulation in the cow and other similar species
- Formation of Corpus hemorrhagicum
- FSH levels increase (formation and growth of follicles)
- contractions in the uterus
What happens during Diestrus?
- high progesterone levels
- FSH rises at a certain point to enable the ovulating follicle to grow
- Contractions stop in the uterus
- small corpus luteum at end of period if not pregnant - due to release of PGF
Canine estrus cycle:
Anestrus - __Months
(Follicular phase)
Proestrus - __ days
Estrus - ___ days
(Luteal phase)
Diestrus - ___ months
Anestrus - 5 Months
(Follicular phase)
Proestrus - 9 days
Estrus - 9 days
(Luteal phase)
Diestrus - 2 months
What is anestrus?
Anestrus refers to the phase when the sexual cycle rests. This is typically a seasonal event and controlled by light exposure through the pineal gland that releases melatonin
Amenorrhea in women
the absence of menstruation during the reproductive years of a woman’s life
- prolonged reproductive cycle , seen in athletes and during lacation
What are gonadotropin hormones?
FSH, LH, and Prolactic
What is the Placenta hormone produced in mares called and its use?
Equine Chorionic Gonadotropin - formation of accessory Corpus Luteum and pregnancy maintence
What is the job of Prostaglandin hormone PGF2a?
contracts blood vessels, corpus luteum breakdown, sperm motility, parturition (act of giving birth)
What is the job of Prostaglandin hormone PGE2a?
Expands blood vessels, ovulation, corpus luteum maintenance, fetal implantation
What does puberty begin with?
begins with the ability of sepcific hypothalamic neurons to provide enough GnRH to promote and support gametogensis
When is considered female puberty?
- age at 1st estrus cycle
- age at first ovulation
- age @ which the female can keep a pregnancy **
When is considered male puberty?
- age at which male behavior begin to be expressed
- age of first ejaculation
- age at which sperm is first seen in the ejaculate
- age at which sperm is first seen
- age at which sperm is first seen in the urine
- age at which there is a threshold number of sperm in the ejaculate
Age of puberty in Bovine
Male and Female - 11 months
Age of puberty in Ovine (sheep)
Male and Female at 7 months
Age of puberty in Equine
Male 14 months and Female 18 months
- horses are seasonal cycle - a large range because sexual maturity is in the spring (those born in the fall are sexually mature only in the following spring
What effects puberty?
hormones, genetics, environment, nutrition
What hormone determines the time of puberty?
GnRH
What are potential inspectors of GnRH pulses during puberty?
- development of surge center
- change in feedback sensitivity to estradiol
When is puberty in birds?
at 2 months of age (zebra finch, japanese quail)
- Song birds and parrots at one year
- larger birds around 3 years
- males later then females
When is puberty in rodents such as ferret?
Females - 8-12 months
Males - 4-12 months
Seasonal Breeders - long day!
Monoestrus
cycle once or twice a year
In Bitches cycle twice a year
In Wolves once a year