Endocrine System & Hormones Flashcards
What major processes are controlled by hormones
Reproduction, growth and development, mobilizing body defences against stressors, maintain electrolyte, water and nutrient balance of the blood, regulating cellular metabolism and energy balance
How does the endocrine system work
uses chemical messengers called hormones, which are released into the blood to be transported leisurely throughout the body
Define Hormones
Chemical substance secreted by cells into the extracellular fluids, that regulate the metabolic activity of other cells in the body.
What is amines
Organic compound that binds to what it needs in that area
What 2 ways can hormones be classified as
Amino acid-based molecules (including proteins, peptides and amines) or steroids (made by gonads and hormones produced by adrenal cortex)
Steroidal hormones trigger changes in cell by (6)
- Diffuse through the plasma membranes of their target cells.
- enters nucleus
- Binds to specific receptor protein
- hormone-receptor binds to specific sites on DNA
- activates certain genes to transcribe mRNA
- mRNA is translated in the cytoplasm, resulting in synthesis of new proteins.
Non-steroidal hormones trigger changes in cell by (4)
- hormone binds to membrane receptor
- setting off series of reactions that activates enzymes which
- catalyzes a reaction that produces a second messenger molecule (AMP) that
- oversees additional intracellular changes that promotes typical response of target cell to the hormone.
What is the meaning of Hormone
To arouse
Explain Direct Gene Activation (6)
Steroids use this. Being a lipid-soluble molecules, it can:
- diffuse through the plasma membranes of their target cells.
- enters the nucleus
- binds to a specific hormone receptor
- hormone-receptor complex then binds to specific sites on the cells DNA
- activating certain genes to transcribe mRNA
- mRNA is translated in the cytoplasm, resulting in the synthesis of new proteins
Explain second-messenger system (4)
Peptides bind to hormone receptors situated on target cells plasma membrane.
- the hormone binds to the membrane receptor
- activated receptor sets off a series of reactions that activates an enzyme
- enzyme catalyzes reactions that produce second messenger molecules that
- oversee additional intracellular changes that promote the typical response of the target cell to the hormone.
What determines whether a hormone will influence a given body cell
A hormone can influence a body cell only if that cell has receptors for that hormone on its plasma membrane or internally.
Why is it important that signal triggering a pain response come from the nervous system and not the endocrine
The endocrine system delivers commands slowly via hormones where as the nervous system uses electrical messages that are much faster
What is a hormone and a target organ
Hormone is a chemical messenger. Target organ of a hormone is the specific cell or tissue that the hormone affects
What major endocrine organ is part of the nervous system
Hypothalamus
What are two important differences between endocrine and exocrine glands
Endocrine glands are ductless and release their hormones into the interstitial fluid. Exocrine glands empty through ducts to an epithelial surface
Name the hormones of the Anterior Pituitary (6)
Growth Hormone (GH), Prolactin (PRL), Thyrotropic Hormone /Thyroid-stimulating hormone (TH) or (TSH), Adrenocorticotropic hormone(ACTH), 2 gonadotropic hormones: Follicle-stimulating hormone (FSH) and Lutenizing hormone (LH)
Why is the Posterior pituitary not an endocrine gland
It is used for storage of the hormones made by the hypothalmus.
What hormones does the pituitary gland release
Oxytocin and Antidiuretic homone (ADH)
What are the hormones of the Thyroid
T3(Triiodothyronine), T4 (Thyroxine), Calcitonin
Why is iodine important for proper thyroid gland function
Functional thyroid hormone has iodine as part of its structure
What does calcitonin do
Deposits calcium in bones. Ceases to work in adults.