Endocrine System Drill Flashcards
Characteristics of Polypeptide hormone activity
- Target organ is distant from site of release
- Transmission via blood circulation
- Cellular effects often require protein kinase activity
- They are large and hydrophilic so they cant pass through a cell membrane
The rate of oxidative metabolism is measured using a basal metabolic rate (BMR) test. If a subject has hyperthyroidism, the rate
will be above normal
-Patients with hyperthyroidism produce excess amounts of thyroid hormone, thus increasing their BMR.
what does the adrenal cortex do
Primarily makes cortisol and aldosterone
Which of the following perform endocrine functions A. Thyroid B. Testes C. Pancreas D. Liver
A. B. C. - YES - The pancreas (secretes insulin and glucagon), testes (secrete testosterone), and thyroid (secretes thyroxine) are all endocrine glands.
D. - NO - The liver is an exocrine gland, secreting bile into a duct that travels to the duodenum. Note that the pancreas has exocrine functions in addition to its endocrine role; it synthesizes enzymes and releases them into the duodenum via a duct.
What are some of the effects of the parathyroid hormone?
Primary role of PTH is to increase free calcium levels in the blood
- it promotes osteoclast activity, compared to osteoblast activity
- It increases bone resorption.
- It decreases phosphate excretion in kidneys.
Which hormones are released in the posterior pituitary
oxytocin and ADH
All of the following hormone receptors contain transmembrane domains EXCEPT: A. calcitonin receptors. B. growth hormone receptors. C. cortisol receptors. D. cholecystokinin receptors.
C. Cortisol Receptors - it is a steroid hormone; its receptor would be found in the cytoplasm and would not contain a transmembrane domain.
the others are peptide hormones that bind to cell surface receptors embedded within the plasma membrane and trigger a cascade of effects within the cell.
What hormones are small and hydrophobic and can freely diffuse through the plasma membrane?
steroids