Endocrine System Drill Flashcards

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1
Q

Characteristics of Polypeptide hormone activity

A
  • Target organ is distant from site of release
  • Transmission via blood circulation
  • Cellular effects often require protein kinase activity
  • They are large and hydrophilic so they cant pass through a cell membrane
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2
Q

The rate of oxidative metabolism is measured using a basal metabolic rate (BMR) test. If a subject has hyperthyroidism, the rate

A

will be above normal

-Patients with hyperthyroidism produce excess amounts of thyroid hormone, thus increasing their BMR.

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3
Q

what does the adrenal cortex do

A

Primarily makes cortisol and aldosterone

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4
Q
Which of the following perform endocrine functions
        A.  Thyroid
   	B.  Testes
   	C.  Pancreas
   	D.  Liver
A

A. B. C. - YES - The pancreas (secretes insulin and glucagon), testes (secrete testosterone), and thyroid (secretes thyroxine) are all endocrine glands.

D. - NO - The liver is an exocrine gland, secreting bile into a duct that travels to the duodenum. Note that the pancreas has exocrine functions in addition to its endocrine role; it synthesizes enzymes and releases them into the duodenum via a duct.

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5
Q

What are some of the effects of the parathyroid hormone?

A

Primary role of PTH is to increase free calcium levels in the blood

  • it promotes osteoclast activity, compared to osteoblast activity
  • It increases bone resorption.
  • It decreases phosphate excretion in kidneys.
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6
Q

Which hormones are released in the posterior pituitary

A

oxytocin and ADH

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7
Q
All of the following hormone receptors contain transmembrane domains EXCEPT:
	A.  calcitonin receptors.
   	B.  growth hormone receptors.
   	C.  cortisol receptors. 
   	D.  cholecystokinin receptors.
A

C. Cortisol Receptors - it is a steroid hormone; its receptor would be found in the cytoplasm and would not contain a transmembrane domain.

the others are peptide hormones that bind to cell surface receptors embedded within the plasma membrane and trigger a cascade of effects within the cell.

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8
Q

What hormones are small and hydrophobic and can freely diffuse through the plasma membrane?

A

steroids

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