Endocrine System Chapter 13 Flashcards
Endocrine
Includes cells, tissues, and organs (collectively called endocrine glands) secretes hormones which act on target cells
Local hormones
Paracrine hormone
Autocrine hormone
Paracrine hormone
Released into interstitial for local action
Autocrine hormone
affect only the secreting cell (or self)
Hormone
a biochemical secreted by a cell to affect the function of other cells (or itself) by means of contact or blood transport to these target cells with specific receptors of proteins or glycoprotiens
Functions of hormones
Regulate metabolic processes
control rates of some chemical reactions
Aid in transport through membranes
Regulate water balance, electrolyte balance, BP, reproduction and growth
Types of hormones
Steroid and nonsteroidal
Steroid
Synthesized from cholesterol. Soluble in lipids, diffuse into cells to activate genes on DNA to synthesize specific proteins or can inhibit genes
Prostaglandins
Produced in a wide variety of cells; regulate neighboring cells (paracrine secretions)
Actions of hormones
Alter metabolic processes
Nonsteroid
a hormone that is the first messenger. binds to specific receptor molecule complex on the membrane. This causes its activity site to chemically alter the membrane transport mechanisms.
Control
three different systems but all employ negative feedback. Hormones have half live.
Three control systems
Hormonal
Nervous
Vascular
Hormonal
Hypothalamus->ant pituitary: releases tropic (influencing) hormones stimulating other endocrine glands to release
Nervous
nervous system-> some endocrine glands directly
Vascular
plasma levels-> some endocrine glands directly
Pituitary
At the base of the brain, attached to the hypothalamus via infundibulum. Lies in the sella turcica
Anterior chemical hormonal
the hypothalamus secretes releasing hormones which are carried to the pituitary via the hypophyseal portal veins
5 types of secretory cells in the pituitary
Growth (GH) Prolactin (PRL) Thyroid stimulating (TSH) Adrenocorticotropic (ACTH) Follicle Stimulating (FSH) Luteinizing (LH)
Growth hormone
(somatotropin) stimulates cells to enlarge and rapidly divide, enhances protein synthesis and amino acid transfer through cell membranes. Released if protein deficiency or loooooooooow glucose
Prolactin (PRL)
milk production
Thyroid stimulating (TSH)
Excess levels lead to goiter