Endocrine System Flashcards
ductLESS and secrete directly into the blood
endocrine glands
CONTAIN DUCTS and carry substances directly to a specific target
exocrine glands
major endocrine organs
thyroid organs
adipose tissues
hypothalamus
two categories of hormones
steroid derived hormones
amine and polypeptide hormones
what are amine and polypeptide hormones synthesized from?
amino acids
Hormones alter cellular rxns by altering plasma membrane transport via what?
second messenger system
Hormones alter cellular reactions of specific target cells by what 4 things:
1] MODIFYING rate of intracellular protein synthesis
2] CHANGING rate of enzyme activity
3] ALTERING plasma membrane transport
4] INDUCING secretory activity
Hormones increase enzyme activity by:
stimulating production and combining with the enzyme to change its shape and action
Over the course of exercise, some enzymes increase in #, causing what?
increases ability to produce oxygen and VO2 max
Cyclic AMP: cyclic 3’5’-adenosine monophosphate
important 2nd messenger to amp up cellular response
How do you create a cellular response?
nonsteroid circulating hormone (1st messenger) binds to a receptor in plasma membrane…cyclic amp (2nd messenger) and this activates protein kinase –> target enzyme –> cellular response
4 factors that determine plasma concentration of a hormone:
- amount synthesized in host gland
- rate of either catabolism or secretion into blood
- amount of transport protein present
- changes in plasma volume
patterns of hormone release
as needed; in intervals during 24 hours or monthly cycles, etc
promotes cell division and cellular proliferation throughout the body
growth hormone (GH)
GH facilitates protein synthesis by:
increasing amino acid transport and stimulating RNA formation
slows carbohydrate breakdown and initiates mobilization and use of fat for energy
GH (growth hormone)
indirect actions of GH does what?
promote anabolism and goes to liver and other organs
direct actions of GH does what?
anti-insulin effect; reduces glucose uptake to maintain blood sugar level and goes to adipose tissue
What does ACTH regulate?
adrenal cortex output
- helps maximize fuel source for exercise
enhances FFA mobilization from adipose tissue
increases gluconeogenesis
stimulates protein catabolism
how ACTH regulates
What does prolactin do?
initiates and supports milk secretion from mammary glands in females
PRL levels _________ with intense exercise and return toward baseline within 45 min in recovery
increase
Repeated exercise-induced PRL for women release may ? and contribute to menstrual cycle alterations with intense training for women who do competitions
inhibit ovarian function