Endocrine System Flashcards
What is the function of endocrine glands?
To secrete hormones, which move in blood to their target cell.
What is somatostatin?
Made by delta cells of the pancreas. This will bind to the beta cells of the pancreas to stop insulin production.
What are beta cells?
Cells in the pancreas that make insulin.
What does nitric oxide do in the endocrine system?
It’s in the endothelial cells, cause constriction
What does melatonin do?
Made by tryptophan (an amino acid). Made in the pineal glad to induce sleep.
What are eicosanoids?
Hydrophilic, lipid derivative.
Which hormones are H20 soluble?
- Amino acid derivatives EXCEPT T3 and T4
- Peptide hormones
- Lipid derivatives EXCEPT steroids
Which hormones are Lipid soluble?
Steroids
T3 and T4.
Where do H20 soluble (hydrophilic) hormones find their receptors?
Plasma membrane.
Where do lipid soluble (lipophilic) hormones find their receptors?
Intracellular. Literally anywhere but the plasma membrane.
What are the three stimuli in control of hormone release?
- Humoral stimulus-conc. of particular substances in blood
- Neural stimulus- Dependent upon action potential by the neuron
- Hormonal stimulus- You must have at least two hormones involved.
What three levels does target cell activation depend upon?
- Blood levels of hormone
- Relative number of receptors on/in the target cell.
- Affinity (strength) of binding between receptor and hormone.
