Endocrine system Flashcards
Does the pancreas have endocrine function or exocrine function
Both.
what does the exocrine function of. a pancreas do?
secretes digestive enzymes such as lipase and amylase to digest food
What does the endocrine function of a pancreas do?
it secretes hormones such as insulin and glucagon into the blood stream.
What does insulin do?
It lowers the blood sugar
what does glucagon do?
It raises the blood sugar.
What happens In the event of ineffective glucose utilisation
?
Increase in glucose production
Decrease in glucose utilisation
produce too much to be used
List the Complications of diabetes
Risk for stroke
retinopathy
Cardiovascular disease, HTN,
microvascular damage
Nephropathy
Erectile dysfunction
Delayed healing
high lipids and high glucose
foot damage
Explain type 1 diabetes
Type 1 diabetes patients have damaged beta cells in their pancreas and cannot secrete insulin - need insulin replacement.
cannot be treated with oral anti diabetic medications.
Explain type 1 diabetes
Type 1 diabetes patients have damaged beta cells in their pancreas and cannot secrete insulin - need insulin replacement.
cannot be treated with oral anti diabetic medications.
where is glucose stored?
liver
where is glucose absorbed in?
skeletal muscle
Explain type 2 diabetes
type 2 diabetes are insulin resistant. they may be able to make insulin but cannot use it effectively to get the glucose into the cell to be used as energy.
It can be treated with oral antidiabetics and may progress to the need for insulin replacement
Please explain the causes of diabetes
type 1 A: immune mediated beta cells destruction
type 1B: idiopathic, non immune mediated
Acquired: diffuse damage to beta cells with subsequent insulin deficiency
- can occur from infections or drugs that affect the pancreas
impaired action of insulin secondary to insulin resistance
List the classic hyperglycaemic symptoms
Polyuria- excessive urination
Polyphagia- excessive hunger
Polydipsia- excessive thirst.
what if there is no hyperglycaemic symptoms but the result is high?
repeat test.