Endocrine system Flashcards

1
Q

Does the pancreas have endocrine function or exocrine function

A

Both.

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2
Q

what does the exocrine function of. a pancreas do?

A

secretes digestive enzymes such as lipase and amylase to digest food

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3
Q

What does the endocrine function of a pancreas do?

A

it secretes hormones such as insulin and glucagon into the blood stream.

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4
Q

What does insulin do?

A

It lowers the blood sugar

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5
Q

what does glucagon do?

A

It raises the blood sugar.

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6
Q

What happens In the event of ineffective glucose utilisation
?

A

Increase in glucose production
Decrease in glucose utilisation

produce too much to be used

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7
Q

List the Complications of diabetes

A

Risk for stroke
retinopathy
Cardiovascular disease, HTN,
microvascular damage
Nephropathy
Erectile dysfunction
Delayed healing
high lipids and high glucose
foot damage

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8
Q

Explain type 1 diabetes

A

Type 1 diabetes patients have damaged beta cells in their pancreas and cannot secrete insulin - need insulin replacement.

cannot be treated with oral anti diabetic medications.

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8
Q

Explain type 1 diabetes

A

Type 1 diabetes patients have damaged beta cells in their pancreas and cannot secrete insulin - need insulin replacement.

cannot be treated with oral anti diabetic medications.

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9
Q

where is glucose stored?

A

liver

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10
Q

where is glucose absorbed in?

A

skeletal muscle

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11
Q

Explain type 2 diabetes

A

type 2 diabetes are insulin resistant. they may be able to make insulin but cannot use it effectively to get the glucose into the cell to be used as energy.

It can be treated with oral antidiabetics and may progress to the need for insulin replacement

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12
Q

Please explain the causes of diabetes

A

type 1 A: immune mediated beta cells destruction

type 1B: idiopathic, non immune mediated

Acquired: diffuse damage to beta cells with subsequent insulin deficiency
- can occur from infections or drugs that affect the pancreas

impaired action of insulin secondary to insulin resistance

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13
Q

List the classic hyperglycaemic symptoms

A

Polyuria- excessive urination
Polyphagia- excessive hunger
Polydipsia- excessive thirst.

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14
Q

what if there is no hyperglycaemic symptoms but the result is high?

A

repeat test.

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15
Q

Risk factors for diabetes

A

Impaired glucose metabolism
central obesity
HTN HLD

15
Q

Risk factors for diabetes

A

Impaired glucose metabolism
central obesity
HTN HLD

16
Q

What is ketosis?

A

a normal metabolic state, burn fat as energy.

1-6mmol/L ketones in blood.

17
Q

What is ketoacidoses

A

a dangerous metabolic state, 15-30mmol/L ketones in blood. affects clients with type 1 diabetes

18
Q

what is the normal pH level

A

7.35-7.45

19
Q

what are ketones

A

they are a by product of fat metabolism. they are acidic.

excessive ketones= ketoacidosis and dehydration, imbalance in electrolytes

20
Q

what happens when a type 1 diabetes patient undergo ketosis?

A

Fat is not the best choice of primary energy source for patients with tip 1 diabetes.
without insulin to move glucose into the cells, the body turns to fat stores for the energy.

ketones are then produced as a by product.

21
Q

similarities between DKA and HHNK

A

1) Both occur in clients with diabetes
2. Life-threatening/medical emergencies, elevated blood glucose
3. Increased serum plasma osmolarity (normal: 275 295 mOsm/L)
4. Extreme osmotic diuresis and dehydration

22
Q

Symptoms of DKA

A

1) abdmoninal pain, nausea
2) lethargy
3) kussmaul’s breathing- body is trying to blow off more carbon dioxide to raise the body’s pH
4) fruity breath
5) polyuria, polydipsia
6) hyperkalemia