Endocrine Physiology Flashcards
Anterior pituitary
Acidophilic cells
GH, Prolactin
Anterior pituitary
Basophilic cells
FSH LH ACTH TSH MSH
Most abbundant cells in Ant. Pit?
Somatotropes 40%
Corticotropes 20%
This Ant. Pit hormone is not reduced by lesions in the pituitary stalk
Prolactin - has no releasing hormone, only INHIBITORY hormone - Dopamine
Treatment for Peripheral Diabetes insipidus
Thiazide diuretic
Treatment for SIADH
Demeclocycline (ADH antagonist)
Phenylalanine derivatives
Phenylalanine Tyrosine LDopa Dopamine NE Epinephrine Thyroxine Melanin
Tryptophan derivative
Tryptophan
Melatonin
Serotonin
Niacin
Inhibits Iodine trapping
Perchlorate
Thiocyanate
Steps inhibited by Propylthiouracil
Oxidation of iodine
Organification
Coupling
Thyroid hormones increase O2 consumption and BMR by what mechanism
Increases mitochondria and Na K ATPase pump activity
Tremors in Hyperthyroidism
FINE Muscle tremors
Diabetogenic hormones
Cortisol
GH
Glucagon
Epinephrine
Inhibits 11B hydroxylase in steroidogenesis
Metyrapone
Inhibits Cholesterol desmolase in steroidogenesis
Ketoconazole