Endocrine Pharmacology- WK6 ( CH28-32 )

Question 1

From a physical therapy perspective, the most important adverse effect seen in patients taking systemic glucocorticoid (anti-inflammatory steroid) drugs is:

Answer 1

Tissue Catabolism

Question 2

In postmenopausal women, estrogen replacement may provide beneficial effects on ________, but may also increase the risk of ___________ disease .

Answer 2

Bone, Cardiovascular disease

Question 3

Physical therapists should be aware of the potential adverse effects of the drugs that regulate calcium homeostasis. For instance, excessive doses of calcium supplements may alter cardiovascular function, resulting in ____________ .

Answer 3

Cardiac Arrythmias

Question 4

Insulin _____________ the storage of glucose in skeletal muscle and other tissues, thereby ____________ plasma glucose levels after a meal.

Answer 4

Increase, decreasing

Question 5

The glucocorticoid-induced catabolism of tissues ____________________ ( greater or less than expected ) in the presence of other contributing factors such as inactivity, poor nutrition and the effects of aging.

Answer 5

greater than expected

Question 6

With dehydration, what will happen to each of the following as compared to a normal individual?

Body weight will _____________

Urine output will _____________

______________ likelihood that exercise on a warm day may lead to heat stroke

Heart rate upon standing will ____________

___________ chance of confusion

Answer 6

decrease, decrease, increase, increase, increased

Question 7

Hormonal drugs serve which functions ?

Answer 7

HRT, increase hormonal effects, manipulate hormonal control

Question 8

Acute problems of insulin insufficiency include ________________ followed by ________________

The chronic problem of insulin insufficiency is repeated/prolonged ______________

Answer 8

hyperglycemia, hypoglycemia

hyperglycemia

Question 9

An adverse effect of insulin therapy is hypoglycemia. This can occur due to :

Answer 9

dose of insulin being too high, delayed/missed meal, strenous exercise

Question 10

The primary pharmacologic strategies for treating type 2 diabetes include:

Answer 10

increase insulin secretion and supply, sensitize tissues to insulin

Question 11

Exercise is a critical part of the management in type 1 and type 2 diabetes. For patient’s with type 2 diabetes, regular exercise could improve health, and reduce or even eliminate the need for meds. ( T/F)

Answer 11

True

Question 12

What are the side effects of anabolic steroid abuse ?

Answer 12

liver damage, cardiovascular disease, abnormal bone metabolism, mood swings, aggression, altered sexual function

Question 13

while estrogen replacement has the beneficial effects of improving bone mineralization, there are some serious risks associated with it. What are those risks ?

Answer 13

Cancer , stroke, DVT

Question 14

The primary effects of thyroid hormones include:

produce general _________in metabolism

__________ cell metabolism

___________ body temperature

___________ cardiac output, respiration

Answer 14

increase x4

Question 15

The rehab concerns for patient’s who are on thyroid replacement therapy is to monitor for signs of over and underdosing.

___________ mimics hyperthyroidism.

____________ mimics hypothyroidism

Answer 15

too much, too little

Question 16

Describe chronic hyperglycemia caused angiopathy.

Answer 16

repeated and prolonged hyperglycemia can lead to occlusion of blood vessels when glucose binds to proteins in vessel wall, this occlusion inhibits blood flow to tissues like the nerves, retina in the eye, kidneys